Results 41 to 50 of about 99,329 (223)

Regulation of NMDA Receptor Signaling at Single Synapses by Human Anti-NMDA Receptor Antibodies

Frontiers in Molecular Neuroscience, 2022
The NMDA receptor (NMDAR) subunit GluN1 is critical for receptor function and plays a pivotal role in synaptic plasticity. Mounting evidence has shown that pathogenic autoantibody targeting of the GluN1 subunit of NMDARs, as in anti-NMDAR encephalitis ...
Charles A. Dean, Sarah R. Metzbower, Scott K. Dessain, Thomas A. Blanpied, David R. Benavides   +4 more
doaj   +1 more source

REDUCING PERIPHERAL INFLAMMATION WITH INFLIXIMAB REDUCES NEUROINFLAMMATION AND IMPROVES COGNITION IN RATS WITH HEPATIC ENCEPHALOPATHY

Frontiers in Molecular Neuroscience, 2016
Inflammation contributes to cognitive impairment in patients with hepatic encephalopathy (HE). However, the process by which peripheral inflammation results in cognitive impairment remains unclear.
Vicente Felipo
doaj   +1 more source

External Electromagnetic Wave Excitation of a PreSynaptic Neuron Based on LIF model [PDF]

arXiv, 2020
Interaction of electromagnetic (EM) waves with human tissue has been a longstanding research topic for electrical and biomedical engineers. However, few numbers of publications discuss the impacts of external EM-waves on neural stimulation and communication through the nervous system.
arxiv  

Membrane Fusion Involved in Neurotransmission: Glimpse from Electron Microscope and Molecular Simulation

Frontiers in Molecular Neuroscience, 2017
Membrane fusion is one of the most fundamental physiological processes in eukaryotes for triggering the fusion of lipid and content, as well as the neurotransmission.
Zhiwei Yang, Zhiwei Yang, Zhiwei Yang, Lu Gou, Shuyu Chen, Na Li, Shengli Zhang, Lei Zhang   +7 more
doaj   +1 more source

The effects of whole-body vibration therapy on immune and brain functioning: current insights in the underlying cellular and molecular mechanisms

Frontiers in Neurology
Whole-body vibration (WBV) therapy is a way of passive exercise in which subjects are exposed to mild and well-controlled mechanical vibrations through a vibrating platform.
Gargi Ahuja, Gargi Ahuja, Y. Laurisa Arenales Arauz, Y. Laurisa Arenales Arauz, Marieke J. G. van Heuvelen, Arjan Kortholt, Tamás Oroszi, Eddy A. van der Zee   +7 more
doaj   +1 more source

Metabolic flux and compartmentation analysis in the brain in vivo

Frontiers in Endocrinology, 2013
Through significant developments and progresses in the last two decades, in vivo localized nuclear magnetic resonance spectroscopy (MRS) became a method of choice to probe brain metabolic pathways in a non-invasive way.
Bernard eLanz, Rolf eGruetter, Rolf eGruetter, Rolf eGruetter, João M.N. Duarte, João M.N. Duarte   +5 more
doaj   +1 more source

In VivoAdenovirus-Mediated Gene Transfer for Parkinson's Disease

Neurobiology of Disease, 1997
Gene therapy is a potentially powerful approach to the treatment of neurological diseases. Neurotransmitter synthesizing enzymes and neurotrophic factors inhibiting neurodegenerative processes provide the basis for current development of gene therapy ...
Philippe Horellou, Alicia Bilang-Bleuel, Jacques Mallet   +2 more
doaj  

Interplay between metabotropic glutamate type 4 and adenosine type 1 receptors modulate synaptic transmission in the cerebellar cortex

Frontiers in Pharmacology
The synapses between parallel fibers and Purkinje cells play a pivotal role in cerebellar function. They are intricately governed by a variety of presynaptic receptors, notably by type 4 metabotropic glutamate (mGlu4) receptors and type 1 adenosine (A1 ...
Simon Bossi, Hervé Daniel, Heather McLean   +2 more
doaj   +1 more source

Optical modulation of neurotransmission using calcium photocurrents through the ion channel LiGluR

Frontiers in Molecular Neuroscience, 2013
A wide range of light-activated molecules (photoswitches and phototriggers) have been used to the study of computational properties of an isolated neuron by acting pre and postsynaptically.
Mercè eIzquierdo-Serra, Dirk eTrauner, Artur eLlobet, Pau eGorostiza, Pau eGorostiza, Pau eGorostiza   +5 more
doaj   +1 more source

Glutamatergic Neurotransmission in Alcoholism

Journal of Biomedical Science, 1998
Substance abuse and dependence is the most common psychiatric problem. Alcohol is the most commonly abused substance and most people who abuse other substance(s) abuse alcohol at the same time ...
openaire   +3 more sources