Results 51 to 60 of about 138,388 (201)

Neuronal Dysfunction and Behavioral Abnormalities Are Evoked by Neural Cells and Aggravated by Inflammatory Microglia in Peroxisomal β-Oxidation Deficiency

Frontiers in Cellular Neuroscience, 2018
It is becoming evident that microglia, the resident immune cells of the central nervous system (CNS), are active contributors in neurological disorders.
Lien Beckers, Stijn Stroobants, Rudi D’Hooge, Myriam Baes   +3 more
doaj   +1 more source

Interplay between metabotropic glutamate type 4 and adenosine type 1 receptors modulate synaptic transmission in the cerebellar cortex

Frontiers in Pharmacology
The synapses between parallel fibers and Purkinje cells play a pivotal role in cerebellar function. They are intricately governed by a variety of presynaptic receptors, notably by type 4 metabotropic glutamate (mGlu4) receptors and type 1 adenosine (A1 ...
Simon Bossi, Hervé Daniel, Heather McLean   +2 more
doaj   +1 more source

Neurotransmission and secretion [PDF]

Nature, 1993
PATARNELLO, TOMASO, BARGELLONI, LUCA, ROSSETTO, ORNELLA, SCHIAVO, GIAMPIETRO, MONTECUCCO, CESARE   +4 more
openaire   +5 more sources

Elucidating the pivotal molecular mechanisms, therapeutic and neuroprotective effects of lithium in traumatic brain injury

Brain and Behavior
Introduction Traumatic brain injury (TBI) refers to damage to brain tissue by mechanical or blunt force via trauma. TBI is often associated with impaired cognitive abilities, like difficulties in memory, learning, attention, and other higher brain ...
Seidu A. Richard
doaj   +1 more source

Beneficial effects of omega-3 fatty acid supplementation in schizophrenia: possible mechanisms

Lipids in Health and Disease, 2020
Background Schizophrenia is a serious long-term psychotic disorder marked by positive and negative symptoms, severe behavioral problems and cognitive function deficits.
Mei-Chi Hsu, Yung-Sheng Huang, Wen-Chen Ouyang   +2 more
doaj   +1 more source

An illustration of possible fast and slow neurotransmission convergence.

, 2013
A. shows that a strong input of fast neurotransmission (which means either large magnitude, long duration, or optimal spacing) causes GluR1 insertion and strong activation of ERK1/2, which may lead to increased protein synthesis and long-term changes (e ...
Kile P. Mangan (379348), Hanoch Kaphzan (379347), Kenneth J. O'Riordan (199412), Jonathan M. Levenson (202312), Kobi Rosenblum (374787)   +4 more
core   +1 more source

Circadian-Like Rhythmicity of Extracellular Brain Glutamate in Epilepsy

Frontiers in Neurology, 2020
Seizures often exhibit striking circadian-like (~24-h) rhythms. While chronotherapy has shown promise in treating epilepsy, it is not widely used, in part because the patterns of seizure rhythmicity vary considerably among patients and types of epilepsy.
Mani Ratnesh S. Sandhu, Roni Dhaher, Shaun E. Gruenbaum, Raaisa Raaisa, Dennis D. Spencer, Milena K. Pavlova, Hitten P. Zaveri, Tore Eid   +7 more
doaj   +1 more source

Role of Calcitonin Gene-Related Peptide in Inhibitory Neurotransmission to the Pig Bladder Neck

, 2011
Purpose: We studied the role of calcitonin gene-related peptide in nonadrenergic, noncholinergic neurotransmission to the pig bladder neck. Materials and Methods: We used immunohistochemical techniques to determine the distribution of calcitonin gene ...
Joaquín Carballido, García-Sacristán, Albino, Hernández Rodríguez, Medardo Vicente, Medardo Hernández, Paz Recio, Ana Martínez-Sáenz, Orensanz, Luis M., Carballido, Joaquín, María Pilar Martínez, Bustamante, Salvador, Luis M. Orensanz, Martínez Sainz, María Del Pilar, Vítor S. Fernandes, Salvador Bustamante, Dolores Prieto, Leite Fernandes, Vitor Samuel, Albino García-Sacristán, Martínez-Sáenz, Ana, Recio Visedo, María Paz, Prieto Ocejo, Dolores   +19 more
core   +1 more source

Mutations affecting glycinergic neurotransmission in hyperekplexia increase pain sensitivity [PDF]

, 2021
See Dickenson (doi:10.1093/brain/awx334) for a scientific commentary on this article. Hyperekplexia is a rare genetic disease resulting in glycine receptor dysfunction.
Schmitt, Bernhard, Arendt-Nielsen, Lars, Fritsche, Raphael, Schliessbach, Jürg, Vuilleumier, Pascal Henri, Curatolo, Michele, Zeilhofer, Hanns Ulrich   +6 more
core  

Dopaminergic neurotransmission - Editorial [PDF]

, 2006
Decades ago, in 1959, dopamine was found to be an essential neurotransmitter. In the years that followed, dopaminergic neurotransmission turned out to be critical for normal motor-, motivational- and reward-related functions.
Westerink, R.H.S.
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