Results 61 to 70 of about 218,364 (416)
Toxoplasma-Induced Hypermigration of Primary Cortical Microglia Implicates GABAergic Signaling
Frontiers in Cellular and Infection Microbiology, 2019 Toxoplasma gondii is a widespread obligate intracellular parasite that causes chronic infection and life-threatening acute infection in the central nervous system.
Amol K. Bhandage +2 more
doaj +1 more source
Rate-limiting recovery processes in neurotransmission under sustained stimulation [PDF]
arXiv, 2023 At chemical synapses, an arriving electric signal induces the fusion of vesicles with the presynaptic membrane, thereby releasing neurotransmitters into the synaptic cleft. After a fusion event, both the release site and the vesicle undergo a recovery process before becoming available for reuse again.
arxiv
Shock Induced Damage Mechanism Of Perineuronal Net [PDF]
, 2021 ECM components, such as the Perineuronal net (PNN), one of the most prevalent parts surrounding the neuronal cell. PNN is a protective net-like structure regulating neuronal activity such as neurotransmission, charge balance and generates an action potential. Shock induced damage of this essential component may cause neuronal cell death and potentially
arxiv +1 more source
Interaction confinement and electronic screening in two-dimensional nanofluidic channels [PDF]
, 2022 The transport of fluids at the nanoscale is fundamental to manifold biological and industrial processes, ranging from neurotransmission to ultrafiltration. Yet, it is only recently that well-controlled channels with cross-sections as small as a few molecular diameters became an experimental reality.
arxiv +1 more source
TMS-EEG signatures of glutamatergic neurotransmission in human cortex
Scientific Reports, 2019 Neuronal activity in the brain reflects an excitation–inhibition balance that is regulated predominantly by glutamatergic and GABAergic neurotransmission, and often disturbed in neuropsychiatric disorders.
Franca König +8 more
semanticscholar +1 more source
TGF-β/Smad3 Signalling Modulates GABA Neurotransmission: Implications in Parkinson’s Disease
International Journal of Molecular Sciences, 2020 γ-Aminobutiryc acid (GABA) is found extensively in different brain nuclei, including parts involved in Parkinson’s disease (PD), such as the basal ganglia and hippocampus.
María Dolores Muñoz +2 more
semanticscholar +1 more source
A Hydrophobic Gate in an Ion Channel: The Closed State of the Nicotinic Acetylcholine Receptor [PDF]
Physical Biology, 3(2):147-159, 2006, 2005 The nicotinic acetylcholine receptor (nAChR) is the prototypic member of the `Cys-loop' superfamily of ligand-gated ion channels which mediate synaptic neurotransmission, and whose other members include receptors for glycine, gamma-aminobutyric acid, and serotonin.
arxiv +1 more source
Neuronal epigenetics and the aging synapse
Frontiers in Cellular Neuroscience, 2015 Two of the most salient phenotypes of aging are cognitive decline and loss of motor function, both of which are controlled by the nervous system. Cognition and muscle contraction require that neuronal synapses develop and maintain proper structure and ...
Benjamin A Eaton, Jorge eAzpurua
doaj +1 more source
Beyond neurotransmission: acetylcholine in immunity and inflammation
Journal of Internal Medicine, 2019 Acetylcholine (ACh) is best known as a neurotransmitter and was the first such molecule identified. ACh signalling in the neuronal cholinergic system has long been known to regulate numerous biological processes (reviewed by Beckmann and Lips).
Maureen A Cox +6 more
semanticscholar +1 more source
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source