Tryptophan research in panic disorder. [PDF]
, 2008 A considerable body of evidence suggests the involvement of serotonin neurotransmission in the pathogenesis of panic disorder. Research on pathways and functions of tryptophan, an essential amino acid converted into serotonin, may advance our ...
Maron, E, Nutt, DJ, Shlik, J
core +5 more sources
Neuronal epigenetics and the aging synapse
Frontiers in Cellular Neuroscience, 2015 Two of the most salient phenotypes of aging are cognitive decline and loss of motor function, both of which are controlled by the nervous system. Cognition and muscle contraction require that neuronal synapses develop and maintain proper structure and ...
Benjamin A Eaton, Jorge eAzpurua
doaj +1 more source
Effects of methamphetamine on locomotor activity and thalamic gene expression in leptin-deficient obese mice [PDF]
, 2017 Leptin is an adipose-derived hormone that regulates energy balance. Leptin receptors are expressed in extrahypothalamic sites and several reports showed that leptin can influence feeding and locomotor behavior via direct actions on dopaminergic neurons ...
Bisagno, Veronica +3 more
core +2 more sources
TMS-EEG signatures of glutamatergic neurotransmission in human cortex
Scientific Reports, 2019 Neuronal activity in the brain reflects an excitation–inhibition balance that is regulated predominantly by glutamatergic and GABAergic neurotransmission, and often disturbed in neuropsychiatric disorders.
Franca König +8 more
semanticscholar +1 more source
Post-training depletions of basolateral amygdala serotonin fail to disrupt discrimination, retention, or reversal learning. [PDF]
, 2015 In goal-directed pursuits, the basolateral amygdala (BLA) is critical in learning about changes in the value of rewards. BLA-lesioned rats show enhanced reversal learning, a task employed to measure the flexibility of response to changes in reward ...
Bugarin, Amador +5 more
core +2 more sources
Beyond neurotransmission: acetylcholine in immunity and inflammation
Journal of Internal Medicine, 2019 Acetylcholine (ACh) is best known as a neurotransmitter and was the first such molecule identified. ACh signalling in the neuronal cholinergic system has long been known to regulate numerous biological processes (reviewed by Beckmann and Lips).
Maureen A Cox +6 more
semanticscholar +1 more source
CD9‐association with PIP2 areas is regulated by a CD9 salt bridge
FEBS Open Bio, EarlyView.The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi +2 more
wiley +1 more source
Neurexin directs partner-specific synaptic connectivity in C. elegans
eLife, 2018 In neural circuits, individual neurons often make projections onto multiple postsynaptic partners. Here, we investigate molecular mechanisms by which these divergent connections are generated, using dyadic synapses in C. elegans as a model.
Alison Philbrook +7 more
doaj +1 more source
Glycine neurotransmission: Its role in development
Frontiers in Neuroscience, 2022 The accurate function of the central nervous system (CNS) depends of the consonance of multiple genetic programs and external signals during the ontogenesis.
Rocío Salceda
doaj +1 more source
Ambient but not local lactate underlies neuronal tolerance to prolonged glucose deprivation [PDF]
, 2018 Neurons require a nearly constant supply of ATP. Glucose is the predominant source of brain ATP, but the direct effects of prolonged glucose deprivation on neuronal viability and function remain unclear.
Mennerick, Steven +3 more
core +3 more sources