Results 201 to 210 of about 60,284 (256)
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Current Opinion in Neurobiology, 1994
In the past year, our knowledge of neurotransmitter transporters has increased significantly. Recently, new members of two families of plasma membrane uptake carriers have been cloned, and the stoichiometries, physiological function and mechanisms of modulation of some of these transporters are now better understood.
M J, Brownstein, B J, Hoffman
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In the past year, our knowledge of neurotransmitter transporters has increased significantly. Recently, new members of two families of plasma membrane uptake carriers have been cloned, and the stoichiometries, physiological function and mechanisms of modulation of some of these transporters are now better understood.
M J, Brownstein, B J, Hoffman
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Mechanism for neurotransmitter-receptor matching [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2020 Synaptic communication requires the expression of functional postsynaptic receptors that match the presynaptically released neurotransmitter. The ability of neurons to switch the transmitter they release is increasingly well documented, and these ...
Nicholas Spitzer
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Cellular and Molecular Neurobiology, 1990
1. To study physiological roles of substance P (SP), gamma-aminobutyric acid (GABA), enkephalins and other endogenous substances, we developed several kinds of isolated spinal cord preparations of newborn rats. 2. In these preparations, various slow responses of spinal neurons evoked by stimulation of primary afferent C fibers were depressed by a ...
M, Otsuka, M, Yanagisawa
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1. To study physiological roles of substance P (SP), gamma-aminobutyric acid (GABA), enkephalins and other endogenous substances, we developed several kinds of isolated spinal cord preparations of newborn rats. 2. In these preparations, various slow responses of spinal neurons evoked by stimulation of primary afferent C fibers were depressed by a ...
M, Otsuka, M, Yanagisawa
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Nanosensors for neurotransmitters
Analytical and Bioanalytical Chemistry, 2015Neurotransmitters are an important class of messenger molecules. They govern chemical communication between cells for example in the brain. The spatiotemporal propagation of these chemical signals is a crucial part of communication between cells.
Elena, Polo, Sebastian, Kruss
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Annual Review of Neuroscience, 1996
Synaptic vesicle exocytosis is rapid and highly localized, which are features that arise from the organization of the presynaptic active zone, where vesicle fusion occurs. Colocalization of calcium channels with the proteins making up the vesicle docking machinery at the active zone, combined with the low affinity and high cooperativity of the calcium ...
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Synaptic vesicle exocytosis is rapid and highly localized, which are features that arise from the organization of the presynaptic active zone, where vesicle fusion occurs. Colocalization of calcium channels with the proteins making up the vesicle docking machinery at the active zone, combined with the low affinity and high cooperativity of the calcium ...
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Essays in Biochemistry, 1998
NO and CO are small gaseous molecules that can be synthesized de novo in neuronal tissue and can diffuse readily through the plasma membrane. NOS inhibitors prevent the induction of LTP in the hippocampus, and studies with NOS knock-out mice and viral overexpression of mutated NOS indicate that the endothelial form of the enzyme is probably responsible
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NO and CO are small gaseous molecules that can be synthesized de novo in neuronal tissue and can diffuse readily through the plasma membrane. NOS inhibitors prevent the induction of LTP in the hippocampus, and studies with NOS knock-out mice and viral overexpression of mutated NOS indicate that the endothelial form of the enzyme is probably responsible
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Neurotransmitters as morphogens
1988Publisher Summary This chapter presents considerable evidence for morphogenetic functions of neurotransmitters during embryonic development, a role that may derive from their appearance early in evolution, still evidenced today by their presence in primitive organisms.
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Archives of General Psychiatry, 1982
The most predictable anxiolytic effects of neurotransmitters are linked to the activation of a gamma-aminobutyric acid (GABA)-ergic subsystem associated with specific benzodiazepine receptors. Recent studies have indicated that subtypes of benzodiazepine receptors may be associated specifically with anxiolytic actions.
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The most predictable anxiolytic effects of neurotransmitters are linked to the activation of a gamma-aminobutyric acid (GABA)-ergic subsystem associated with specific benzodiazepine receptors. Recent studies have indicated that subtypes of benzodiazepine receptors may be associated specifically with anxiolytic actions.
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Biofeedback and Self-Regulation, 1990
In this article definitions of stress and distress are proposed and the relationships between stress and activities of neurohormonal systems explored. The idea is developed that stress is a condition where expectations--whether genetically programmed, established by prior learning, or deduced from circumstances--do not match the current or anticipated ...
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In this article definitions of stress and distress are proposed and the relationships between stress and activities of neurohormonal systems explored. The idea is developed that stress is a condition where expectations--whether genetically programmed, established by prior learning, or deduced from circumstances--do not match the current or anticipated ...
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Neurotransmitters and cognition
2006Cognition deficits have receivedmuch attention over the last two decades. The severe impairment of cholinergic function in dementias, particularly in age-related cognitive decline andAlzheimer’s disease has been indicated. However, loss of cholinergic activity may play a key role in the cognitive symptoms but it cannot clearly demonstrate the entire ...
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