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Chronic tendinopathy is a painful common condition affecting athletes as well as the general population undergoing to tendon overuse. Although its huge prevalence, little is known about tendinopathy pathogenesis, and even cloudier is its treatment ...
Sebastiano Vasta+5 more
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Directed Evolution of Protein-Based Neurotransmitter Sensors for MRI [PDF]
The production of contrast agents sensitive to neuronal signaling events is a rate-limiting step in the development of molecular-level functional magnetic resonance imaging (molecular fMRI) approaches for studying the brain.
A Jasanoff+11 more
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Altered brainstem responses to modafinil in schizophrenia: implications for adjunctive treatment of cognition. [PDF]
Candidate pro-cognitive drugs for schizophrenia targeting several neurochemical systems have consistently failed to demonstrate robust efficacy. It remains untested whether concurrent antipsychotic medications exert pharmacodynamic interactions that ...
Carter, Cameron S+3 more
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Flexible couplings: diffusing neuromodulators and adaptive robotics [PDF]
Recent years have seen the discovery of freely diffusing gaseous neurotransmitters, such as nitric oxide (NO), in biological nervous systems. A type of artificial neural network (ANN) inspired by such gaseous signaling, the GasNet, has previously been ...
Husbands, Phil+3 more
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Hallucinogens: mechanisms and medical complications [PDF]
Thesis (M.A.)--Boston UniversityHallucinogens are drugs that alter consciousness by distorting primarily auditory and visual perception but they can affect any sensory system. Hallucinogens also affect judgment, orientation, memory, or emotion.
Chan, Ryan Harry Alexander
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Mice in ecstasy : advanced animal models in the study of MDMA [PDF]
The party drug 3,4-methylenedioxymethamphetamine -better known as MDMA or ecstasy- has numerous effects on the human body, characterized by a rush of energy, euphoria and empathy.
Stove, Christophe+3 more
core +2 more sources
Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity [PDF]
A series of benzo[b]thiophen-3-ols were synthesised and investigated as potential human monoamine oxidase (hMAO) inhibitors in vitro as well as ex vivo in rat cortex synaptosomes by means of evaluation of 3,4-dihydroxyphenylacetic acid/dopamine (DOPAC/DA)
Alcaro, Stefano+13 more
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Expression of VPAC1 in a murine model of allergic asthma [PDF]
Vasoactive intestinal polypeptide (VIP) is a putative neurotransmitter of the inhibitory non-adrenergic non-cholinergic nervous system and influences the mammalian airway function in various ways.
Braun, Armin+4 more
core
Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management
Michele Fornaro, Matteo MartinoDepartment of Neuroscience, Section of Psychiatry, University of Genova, Genova, ItalyBackground: Subjective tinnitus is a frequent, impairing condition, which may also cause neurotransmitter imbalance at the cochlea ...
Michele Fornaro, Matteo Martino
doaj
The norepinephrine transporter (NET) is a Na+/Cl− coupled neurotransmitter transporter responsible for reuptake of released norepinephrine (NE) into nerve terminals in the brain, a key therapeutic used in the treatment of psychiatric disorders.
Sabitu Babatunde Olasupo+3 more
doaj +1 more source