Results 201 to 210 of about 156,401 (247)

Non-steroidal anti-inflammatory agents, tolmetin and sulindac, inhibit liver tryptophan 2,3-dioxygenase activity and alter brain neurotransmitter levels

open access: closedLife Sciences, 2006
Hepatic tryptophan 2,3-dioxygenase (TDO) is one of the rate-limiting enzymes in tryptophan catabolism and plays an important role in regulating the physiological flux of tryptophan into relevant metabolic pathways. In this study, we determined the effect of the non-steroidal anti-inflammatory agents, tolmetin and sulindac, on rat liver TDO activity and
Amichand Dairam   +3 more
openalex   +5 more sources

Interaction of psychotropic agents with central neurotransmitters as revealed by their effects on PGO waves in the cat.

open access: closedArzneimittel-Forschung, 1976
One of the phasic phenomena of REM (rapid eye movement) sleep, the ponto-geniculo-occipital (PGO) waves, are induced in cats by either depleting brain monoamines with the benzoquinolizine derivative Ro 4-1284 or inhibiting the synthesis of 5-hydroxy-tryptamine (5-HT) by p-chlorophenylalanine (PCPA). The effects of the most important psychotropic agents
W Haefely   +3 more
openalex   +3 more sources
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Using the neurotransmitter serotonin to target imaging agents to glioblastoma cells

Investigational New Drugs, 2012
The neurotransmitter serotonin is involved in numerous bodily functions via seven different serotonin receptor subfamilies. Serotonin plays a role in gastrointestinal functions like intestinal secretion or peristalsis and neuropsychiatric events like depression or migraine.
Sturzu, Alexander   +9 more
openaire   +4 more sources

A catecholamine neurotransmitter: epinephrine as a CO2 wet scrubbing agent

Chemical Communications, 2019
Adrenaline can be used to capture CO2 when dissolved in DMSO.
Ala'a F. Eftaiha   +4 more
openaire   +3 more sources

Effect of antidepressant agents on β-adrenergic receptor and neurotransmitter regulatory systems

Pharmacology Biochemistry and Behavior, 1980
Abstract The effects of established and several novel antidepressant agents on brain monoamine oxidase A and B; high affinity synaptosomal uptake of norepinephrine, dopamine and serotonin; and β-adrenergic receptor kinetics evaluated by (3H)-dihydroalprenolol binding to cortical membranes are described.
Laurence R. Meyerson   +3 more
openaire   +3 more sources

The GABA Paradox

Journal of Neurochemistry, 1999
Abstract : GABA, which is present in the brain in large amounts, is distributed among distinctly different cellular pools, possibly reflecting its multiple functions as metabolite, neurotransmitter, and neurotrophin. Its metabolic enzymes also exhibit heterogeneity, because glutamate decarboxylase exists in two isoforms with different subcellular ...
Helle S. Waagepetersen   +2 more
openaire   +3 more sources

Mesoporous, anisotropic nanostructures from bioinspired polymeric catecholamine neurotransmitters and their potential application as photoacoustic imaging agents

Journal of Materials Chemistry B, 2022
Different process parameters can be used to fabricate polydopamine, polynorepinephrine, and polyepinephrine nanospheres and mesoporous nanomaterials (golf balls and bowls) with structure-dependent performance as photoacoustic imaging agents.
Zhenzhen Lu   +5 more
openaire   +2 more sources

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