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Hepatic tryptophan 2,3-dioxygenase (TDO) is one of the rate-limiting enzymes in tryptophan catabolism and plays an important role in regulating the physiological flux of tryptophan into relevant metabolic pathways. In this study, we determined the effect of the non-steroidal anti-inflammatory agents, tolmetin and sulindac, on rat liver TDO activity and
Amichand Dairam+3 more
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One of the phasic phenomena of REM (rapid eye movement) sleep, the ponto-geniculo-occipital (PGO) waves, are induced in cats by either depleting brain monoamines with the benzoquinolizine derivative Ro 4-1284 or inhibiting the synthesis of 5-hydroxy-tryptamine (5-HT) by p-chlorophenylalanine (PCPA). The effects of the most important psychotropic agents
W Haefely+3 more
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Neurotoxic and Neurotrophic Effects of GABAergic Agents on Developing Neurotransmitter Systems
Jean M. Lauder, Jiangping Liu
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Changes in Neurotransmitter Values with Inhalational Agents
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Using the neurotransmitter serotonin to target imaging agents to glioblastoma cells
Investigational New Drugs, 2012The neurotransmitter serotonin is involved in numerous bodily functions via seven different serotonin receptor subfamilies. Serotonin plays a role in gastrointestinal functions like intestinal secretion or peristalsis and neuropsychiatric events like depression or migraine.
Sturzu, Alexander+9 more
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A catecholamine neurotransmitter: epinephrine as a CO2 wet scrubbing agent
Chemical Communications, 2019Adrenaline can be used to capture CO2 when dissolved in DMSO.
Ala'a F. Eftaiha+4 more
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Effect of antidepressant agents on β-adrenergic receptor and neurotransmitter regulatory systems
Pharmacology Biochemistry and Behavior, 1980Abstract The effects of established and several novel antidepressant agents on brain monoamine oxidase A and B; high affinity synaptosomal uptake of norepinephrine, dopamine and serotonin; and β-adrenergic receptor kinetics evaluated by (3H)-dihydroalprenolol binding to cortical membranes are described.
Laurence R. Meyerson+3 more
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Journal of Neurochemistry, 1999
Abstract : GABA, which is present in the brain in large amounts, is distributed among distinctly different cellular pools, possibly reflecting its multiple functions as metabolite, neurotransmitter, and neurotrophin. Its metabolic enzymes also exhibit heterogeneity, because glutamate decarboxylase exists in two isoforms with different subcellular ...
Helle S. Waagepetersen+2 more
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Abstract : GABA, which is present in the brain in large amounts, is distributed among distinctly different cellular pools, possibly reflecting its multiple functions as metabolite, neurotransmitter, and neurotrophin. Its metabolic enzymes also exhibit heterogeneity, because glutamate decarboxylase exists in two isoforms with different subcellular ...
Helle S. Waagepetersen+2 more
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Journal of Materials Chemistry B, 2022
Different process parameters can be used to fabricate polydopamine, polynorepinephrine, and polyepinephrine nanospheres and mesoporous nanomaterials (golf balls and bowls) with structure-dependent performance as photoacoustic imaging agents.
Zhenzhen Lu+5 more
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Different process parameters can be used to fabricate polydopamine, polynorepinephrine, and polyepinephrine nanospheres and mesoporous nanomaterials (golf balls and bowls) with structure-dependent performance as photoacoustic imaging agents.
Zhenzhen Lu+5 more
openaire +2 more sources