Elucidating the Role of Neurotensin in the Pathophysiology and Management of Major Mental Disorders
Behavioral Sciences, 2014 Neurotensin (NT) is a neuropeptide that is closely associated with, and is thought to modulate, dopaminergic and other neurotransmitter systems involved in the pathophysiology of various mental disorders.
Mona M Boules +3 more
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Nitric oxide and synaptic function [PDF]
, 1994 The free radical gas nitric oxide (NO) is a recently identified neuronal messenger that carries out diverse signaling tasks in both the central and peripheral nervous systems.
Madison, Daniel V., Schuman, Erin M.
core +1 more source
Advances in the Preclinical Study of Some Flavonoids as Potential Antidepressant Agents
Scientifica, 2018 Flavonoids are phenolic compounds found commonly in plants that protect them against the negative effects of environmental insults. These secondary metabolites have been widely studied in preclinical research because of their biological effects ...
León Jesús Germán-Ponciano +3 more
semanticscholar +1 more source
Neurochemical Modulating Effect of Boswellia serrata Roxb. ex Colebr: A Preclinical Research
Pharmaceutical and Biomedical Research, 2022 Background: Boswellia serrata has been known for many decades and mentioned in the ancient Ayurvedic texts. Many previous studies have demonstrated its role in depression and anxiety in animal models.
Prabhakar Adake +2 more
doaj
The influence of non-neuronal cells on catecholamine and acetylcholine synthesis and accumulation in cultures of dissociated sympathetic neurons [PDF]
, 1974 The effects of several non-neuronal cell types on neurotransmitter synthesis in cultures of dissociated sympathetic neurons from the new-born rat were studied.
Chun, Linda L. Y., Patterson, Paul H.
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Local and global spontaneous calcium events regulate neurite outgrowth and onset of GABAergic phenotype during neural precursor differentiation [PDF]
, 2003 Neural stem cells can generate in vitro progenitors of the three main cell lineages found in the CNS. The signaling pathways underlying the acquisition of differentiated phenotypes in these cells are poorly understood.
Berridge, Michael J. +5 more
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Biomolecules, 2023 Chronic obstructive pulmonary disease (COPD) is a progressive disease characterized by airway limitation and changes in airway structure. It has a high global burden of mortality and morbidity.
Felisbela Gomes, Shih-Lung Cheng
doaj +1 more source
The binding of botulinum neurotoxins to different peripheral neurons [PDF]
, 2017 Botulinum neurotoxins are the most potent toxins known. The double receptor binding modality represents one of the most significant properties of botulinum neurotoxins and largely accounts for their incredible potency and lethality.
Rossetto, O.
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Could dopamine agonists aid in drug development for anorexia nervosa? [PDF]
, 2014 Anorexia nervosa is a severe psychiatric disorder most commonly starting during the teenage-years and associated with food refusal and low body weight. Typically there is a loss of menses, intense fear of gaining weight, and an often delusional quality ...
Frank, Guido KW
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Mechanism of Allosteric Modulation of the Cys-loop Receptors
Pharmaceuticals, 2010 The cys-loop receptor family is a major family of neurotransmitter-operated ion channels. They play important roles in fast synaptic transmission, controlling neuronal excitability, and brain function.
Paul Whiteaker +2 more
doaj +1 more source