Results 61 to 70 of about 156,401 (247)
Estimating the synaptic current in a multi-conductance AMPA receptor model [PDF]
, 2010 A pre-synaptic neuron releases diffusing neurotransmitters such as glutamate that activate post-synaptic receptors. The amplitude of the post-synaptic current, mostly mediated by glutamatergic (AMPARs) receptors, is a fundamental signal that may generate an action potential.
arxiv +1 more source
Local and global spontaneous calcium events regulate neurite outgrowth and onset of GABAergic phenotype during neural precursor differentiation [PDF]
, 2003 Neural stem cells can generate in vitro progenitors of the three main cell lineages found in the CNS. The signaling pathways underlying the acquisition of differentiated phenotypes in these cells are poorly understood.
Berridge, Michael J. +5 more
core +1 more source
Frontiers in Cellular and Infection MicrobiologyInfluenza presents a significant public health threat, as severe cases can lead to excessive inflammation and complications such as pneumonia or acute respiratory distress syndrome.
Yarou Gao +13 more
doaj +1 more source
Root Apex Transition Zone as Oscillatory Zone
Frontiers in Plant Science, 2013 Root apex of higher plants shows very high sensitivity to environmental stimuli. The root cap acts as the most prominent plant sensory organ; sensing diverse physical parameters such as gravity, light, humidity, oxygen and critical inorganic nutrients ...
Frantisek Baluska +2 more
doaj +1 more source
Could dopamine agonists aid in drug development for anorexia nervosa? [PDF]
, 2014 Anorexia nervosa is a severe psychiatric disorder most commonly starting during the teenage-years and associated with food refusal and low body weight. Typically there is a loss of menses, intense fear of gaining weight, and an often delusional quality ...
Frank, Guido KW
core +2 more sources
Biomolecules, 2019 In vivo activation of dopamine D3 receptors (D3Rs) depresses motor activity. D3Rs are widely expressed in subthalamic, striatal, and dendritic dopaminergic inputs into the substantia nigra pars reticulata (SNr).
Marina Rodríguez-Sánchez +9 more
doaj +1 more source
What's a brain: neuroanatomy and neurochemistry of anxiety disorders in dogs [PDF]
, 2011 This review deals with the neurocircuitry of fear and anxiety disorders, with the focus on neuroanatomy and neurochemistry. This knowledge is required to correctly diagnose and treat dogs with anxiety-related behavioral disorders.
Audenaert, Kurt +6 more
core +1 more source
Irregular convergence of mild solutions of semilinear equations [PDF]
J. Math. Anal. Appl., Vo. 472, No. 2 (2019), 1401-1419, 2018 We prove that even irregular convergence of semigroups of operators implies similar convergence of mild solutions of the related semi-linear equations with Lipschitz continuous nonlinearity. This result is then applied to three models originating from mathematical biology: shadow systems, diffusions on thin layers, and dynamics of ...
arxiv +1 more source
Cerebral low-molecular metabolites influenced by intestinal microbiota: a pilot study
Frontiers in Systems Neuroscience, 2013 Recent studies suggest that intestinal microbiota influences gut-brain communication. In this study, we aimed to clarify the influence of intestinal microbiota on cerebral metabolism. We analyzed the cerebral metabolome of germ-free (GF) mice and ex-germ-
Mitsuharu eMatsumoto +6 more
doaj +1 more source
An Intermediate State of the {gamma}-Aminobutyric Acid Transporter GAT1 Revealed by Simultaneous Voltage Clamp and Fluorescence [PDF]
, 2000 The rat {gamma}-aminobutyric acid transporter GAT1 expressed in Xenopus oocytes was labeled at Cys74, and at one or more other sites, by tetramethylrhodamine-5-maleimide, without significantly altering GAT1 function.
Farley, Robert A. +2 more
core +1 more source