Results 171 to 180 of about 169,266 (282)

Altered Habenula Resting-State Functional Connectivity and Spatial Associations with Neurotransmitter Receptor Distribution of Major Depressive Disorder with and without Anhedonia. [PDF]

Neuropsychiatr Dis Treat
Luo X, Wu Y, Yuan L, Wang Y, Li J, Xu P, Lian J, Liu X, Shen Z.   +8 more
europepmc   +1 more source

Neurotransmitter transporters and their impact on the development of psychopharmacology

British Journal of Pharmacology, 2006
L. Iversen
semanticscholar   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

Journal of Applied Toxicology, EarlyView.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz, Bayram Göktaş, İlker Ateş, Mustafa Çelik   +3 more
wiley   +1 more source

Tannic Acid Mitigates Monosodium Glutamate‐Induced Cortical Damage by Modulating Synaptic and Calcium‐Related Gene and Protein Expression

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac, Enver Fehim Koçpinar, Hamid Ceylan   +2 more
wiley   +1 more source

Pharmacological interventions targeting the gut-brain axis in neurological disorders: mechanisms and translational applications. [PDF]

Front Neurosci
Li X, Zhou W, Yang S, Huang X, Zheng K.
europepmc   +1 more source

Formulation‐Dependent Cytotoxic Effects of Commercial and Analytical‐Grade Mancozeb in C6 Glial Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Mancozeb (MZ) is a widely used dithiocarbamate fungicide composed of manganese (Mn) and zinc (Zn) complexes. Increasing concern has been raised regarding its occupational and human health relevance, particularly due to its neurotoxic potential associated with Mn‐related cellular dysfunction.
Lavínia Lazzarotti, Felipe Vanz, Karina Giacomini Varela, Viviane Glaser, Diego de Carvalho, Aline Pertile Remor   +5 more
wiley   +1 more source

Glutamatergic Neurotransmission Disruption as a Pathomechanism of Brain Damage in Disorders of Amino Acid and Organic Acid Metabolism: Insights from Animal and Cellular Studies. [PDF]

Neurochem Res
Marcuzzo MB, Benati MPDV, Souza DO, Wajner M, Leipnitz G.   +4 more
europepmc   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Tumor-associated epilepsy and high expression of xCT shape the proteome of IDH-wildtype glioblastoma. [PDF]

Cell Death Discov
Divé I, Schäfer JA, Weber KJ, Çakır AY, Verheyden NA, Lorenz NI, Chong SA, Zeiner PS, Franiczek C, Sauer B, Adrian-Allgood M, Urban H, Luger AL, Wenger KJ, Strzelczyk A, Rosenow F, Streffer J, Prinz V, Brucker DP, Dedeurwaerdere S, André VM, Steinbach JP, Buettner F, Münch C, Ronellenfitsch MW.   +24 more
europepmc   +1 more source

Selective serotonin reuptake inhibitors pathway.

Pharmacogenetics & Genomics, 2009
K. Sangkuhl, T. Klein, R. Altman
semanticscholar   +1 more source