Results 271 to 280 of about 183,502 (305)

[Neurotrophic effects of senegenin].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2016
To study the neurotrophic effects of senegenin on the expression of MAP2 mRNA and BDNF mRNA in cultured cerebral cortical neurons.The newborn rat cerebral cortex neurons were cultured in vitro. LDH assay was used to investigate the effect of senegenin on the neuronal viability and reverse transcription polymerase chain reaction (RT-PCR) was carried out
Ting, Pi, Xiao-Yan, Xue, Huan-Min, Luo
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NS-417, a Novel Compound with Neurotrophic-Like Effects

Neurochemical Research, 2002
NS-417 (5-(4-Chlorophenyl)-8-methyl-6-7-8-9-tetrahydro-1-H-pyrrolo[3.2-h]isoquinoline-2,3-dione-3-oxim hydrochloric acid salt) belongs to a new chemical series of compounds. NS-417 rescued differentiated PC12 cells from death induced by withdrawal of serum and nerve growth factor.
Dagø, Lone, Peters, Dan, Meyer, Morten, Hartz, Barbara, Kruse, Vibeke, Drejer, Jørgen, Grønborg, Mette   +6 more
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Neurotrophic Effect on Isolated Chick Embryo Muscle in Culture

Science, 1972
Acetylcholinesterase activity in cultures of dissociated skeletal muscle prepared from the thigh muscle of the 10-day-old chick embryo was increased by the presence of innervating spinal cord explants, spinal cord explants in a parabiotic environment, and by media containing brain-spinal cord extract.
T H, Oh, D D, Johnson, S U, Kim
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Promoting neurotrophic effects by GPCR ligands.

Novartis Foundation symposium, 2006
The neurotrophins-nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), NT-3 and NT-4-represent a family of proteins essential for neuronal survival and plasticity. Each neurotrophin can signal through two different transmembrane receptors, Trk receptor tyrosine kinases and the p75 neurotrophin receptor, the first member of the TNF ...
Freddy, Jeanneteau, Moses V, Chao
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Screening of adrenal medullary neuropeptides for putative neurotrophic effects

International Journal of Developmental Neuroscience, 1992
AbstractChromaffin granules, the secretory organelles of the neuron‐like adrenal medullary chromaffin cells, have previously been shown to store and liberate neurotrophic activities that support in vitro survival of several neuron populations including those innervating the adrenal medulla.
K, Unsicker, F, Stögbauer
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Neurotrophic and Neuroprotective Effects of hAPP in Transgenic Micea

Annals of the New York Academy of Sciences, 1996
To better understand the role the human amyloid precursor protein (hAPP) plays in Alzheimer's disease (AD), it is essential to define its primary function(s). Here we expressed different hAPPs in neurons of transgenic (tg) mice to characterize their effects on the intact central nervous system (CNS).
L, Mucke, C R, Abraham, E, Masliah
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Sphingolipids from Bombycis Corpus 101A and Their Neurotrophic Effects

Journal of Natural Products, 2003
Three new (2-4) and one known (1) sphingolipid were identified in the MeOH extract of Bombycis Corpus 101A. Their structures were elucidated as (4E,2S,3R)-2-N-octadecanoyl-4-tetradecasphingenine (1), (4E,6E,2S,3R)-2-N-eicosanoyl-4,6-tetradecasphingadienine (2), (4E,2S,3R)-2-N-eicosanoyl-4-tetradecasphingenine (3), and (4E,6E,2S,3R)-2-N-docosanoyl-4,6 ...
Hak Cheol, Kwon, Kang Choon, Lee, Ock Ryun, Cho, I Yeon, Jung, Sae Yun, Cho, Sun Yeou, Kim, Kang Ro, Lee   +6 more
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Neurotrophic control of colchicine effects on muscle?

Nature, 1974
COLCHICINE, a substance known to block axonal transport1,2, has been reported to mimic the effects of denervation on mammalian skeletal muscles3–5. These effects, which include an increased extrajunctional sensitivity to acetylcholine (Ach) and a fall in resting membrane potential, occur a few days after colchicine is applied locally to the nerve in ...
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Brain-derived neurotrophic factor

Neurology, 2015
Brain-derived neurotrophic factor (BDNF) is the most ubiquitous and intensively studied member of the family of neurotrophins in the CNS. The transcriptional regulation of BDNF is complex and involves both epigenetic control and transcription factors.
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Ciliary neurotrophic factor (CNTF): physiological and pharmacological effects

Restorative Neurology and Neuroscience, 1995
Sendtner, M., Hughes, R., Dittrich, F., Holtmann, B., Masu, Y., Carroll, P., Ochs, G., Toyka, K., Thoenen, H.   +8 more
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