Results 181 to 190 of about 4,508,815 (293)

Oral Bacterial Extracellular Vesicles as Systemic Messengers: A Mouth–Gut–Systemic Axis Paradigm

Gut Medicine, EarlyView.
ABSTRACT Oral microbiome dysbiosis not only associated with localized periodontal disease but also with multiple systemic diseases, including cardiovascular disease, diabetes mellitus, Alzheimer's disease, rheumatoid arthritis, and cancer. However, the efficiency with which intact viable bacteria cross biological barriers to reach distant organs is ...
Yaping Huang, Narisu Hu, Shuang Pan, Sohaib Shujaat, Zhihui Tang, Hongyang Ma   +5 more
wiley   +1 more source

Effects of Transcranial Direct Current Stimulation Versus Sham Stimulation on Brain-Derived Neurotrophic Factor and Clinical Outcomes: A Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Addas K, Aldabbagh A, Balloura J, Al Raiy A, Balafkhar RM, Othman LS, Aldowairej K, Al-Amoudi OA, Alotaibi MM, Aldehaim FM, Sibyani H, Alshahrani BM, Alnwiji A, Jasim Y, Mohamed AMA.   +14 more
europepmc   +1 more source

Immunotherapy for Head and Neck Cutaneous Squamous Cell Carcinoma with Perineural Spread: A Systematic Review

Head &Neck, EarlyView.
ABSTRACT Background Immunotherapy is increasingly used for head and neck cutaneous squamous cell carcinoma (cSCC) with perineural spread (PNS), though outcomes remain poorly defined. Methods A systematic review was conducted according to PRISMA and MOOSE guidelines.
Jai Paris, James Tsimiklis, Ayushi Agarwal, Jessica Y. Tong, Dinesh Selva   +4 more
wiley   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Graphene Oxide-Modified Titanium Dioxide Nanotubes Promote Schwann Cell Function and Neurotrophic Factor Expression. [PDF]

J Funct Biomater
Cao X, Wang C, Lu R, Mu Y, Hu J, Luo B, Chen S.   +6 more
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Neuron-specific enolase and brain-derived neurotrophic factor as developmental neurovascular markers in chronic kidney disease and kidney transplantation. [PDF]

Pediatr Nephrol
Hernandez L, Strizzi CT, Lindblad YT, Stenvinkel P, Barany P, Chromek M, Kublickiene K.   +6 more
europepmc   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

Correction to: Brain-Derived Neurotrophic Factor rs6265 polymorphism is associated with severe cancer-related fatigue and neuropathic pain in female cancer survivors. [PDF]

J Cancer Surviv
Goto T, Von Ah D, Li X, Xiang L, Kwiat C, Nguyen C, Hsiao CP, Saligan LN.   +7 more
europepmc   +1 more source

A Multimodal Deep Learning Framework Integrating Tumor Microenvironment Niches for Overall Survival Prediction in Esophageal Squamous Cell Carcinoma

iMetaMed, EarlyView.
The training cohort (n = 273) and internal validation cohort (n = 63) were obtained from Qilu Hospital of Shandong University, while the external validation cohort (n = 114) was derived from Liaoning Cancer Hospital. Multimodal input data included CT images with corresponding tumor segmentation masks, whole‐slide pathology images (WSIs), clinical data,
Yuanyue Zhang, Xiaoyan Li, Henan Zhang, Guang Yang, Chulong Zhang, Xiaomin Ni, Xuefei Lin, Huahui Li, Yan Min, Wei Teng, Yaoqin Xie, Hui Yang, Yang Zhang, Xin Hong, Md Tauhidul Islam, Shunsuke Koga, Zhihao Xie, Ping Zhou, Jingdong Zhang, Hao Yu, Xiaokun Liang, Jianbo Wang   +21 more
wiley   +1 more source