Results 121 to 130 of about 115,306 (252)

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

Interdisciplinary Medicine, EarlyView.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen, Jiayi Wang, Jimin Yu, Yiran Zhou, Lihai Liu, Jing Liu, Liang Wang   +6 more
wiley   +1 more source

Engineered 3D cultured human nasal mucosa mesenchymal stem cell derived sEVs for targeted brain‐derived neurotrophic factor delivery to enhance neurogenesis and attenuate brain damage

Interdisciplinary Medicine, EarlyView.
This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang, Junge Chen, Jiao Xia, Weitong Yang, Teng Ma, Tianzi Shan, Weifeng He, Gaoman Zhang, Zhuoran Xia, Weiwei Wang, Zhusheng Liu, Zhiqiang Yi, Piye Niu, Tian Chen   +13 more
wiley   +1 more source

Neurotrophic Factors: Emerging Biology and Therapeutic Applications for Cardiovascular Diseases. [PDF]

Metabolites
Liu Y, Zhang H, Yu F, Liu T, Jia D, Wang R.   +5 more
europepmc   +1 more source

Developmental and Behavioral Effects of Arsenobetaine in Zebrafish (Danio rerio)

Journal of Applied Toxicology, EarlyView.
ABSTRACT Arsenobetaine (AsB) is a prevalent organoarsenical in aquatic environments and is generally regarded as nontoxic. Despite its widespread occurrence, the developmental and neurobehavioral toxicity of AsB has not been systematically investigated.
Sravan Kumar Putnala, Prerita Sharma, Prannav Jain, Samira Leila Baldin, Owen Luo, A. K. M. Munzurul Hasan, Md Helal Uddin, Mahesh Rachamalla, Som Niyogi   +8 more
wiley   +1 more source

Hypothalamic-pituitary-adrenal axis activity and neurotrophic factors in drug-naive children and adolescents with attention-deficit/hyperactivity disorder. [PDF]

Front Psychiatry
Ferahkaya H, Uzun N, Ağır H, Kılınç İ, Akkuş A, Coşkun F, Akça ÖF, Bilgiç A.   +7 more
europepmc   +1 more source

Transcription Pattern of Neurotrophic Factors and Their Receptors in Adult Zebrafish Spinal Cord. [PDF]

Int J Mol Sci, 2023
Cacialli P, Ricci S, Lazzari M, Milani L, Franceschini V.   +4 more
europepmc   +1 more source

Delivery Routes and Anesthesia Affect Cord Blood NGF, BDNF, and Neonatal Outcomes

Journal of Clinical Laboratory Analysis, EarlyView.
Nerve growth factor (NGF) and brain‐derived neurotrophin (BDNF) play a role in brain maturation. Cord blood values do not differ between vaginal delivery and CS cases. In CS cases with spinal anesthesia, high BDNF and NGF values were associated with high cord blood pH and APGAR scores.
Şükran Doğru, Huriye Ezveci, Fikriye Karanfil Yaman, Pelin Bahçeci, Zeynep Şenol, İbrahim Kılınç, Kazım Gezginç   +6 more
wiley   +1 more source

Application of Neurotrophic Factors as a Therapeutic Approach for Neurodegenerative Diseases. [PDF]

Exp Neurobiol
Kim SC, Lee SY, Jung UJ, Kim SR.
europepmc   +1 more source

Aerobic Exercise, Training Dose, and Cardiorespiratory Fitness: Effects and Relationships with Resting Plasma Neurotrophic Factors in Alzheimer's Dementia. [PDF]

J Vasc Dis, 2023
Salisbury DL, Li D, Todd M, Ng TKS, Yu F.   +4 more
europepmc   +1 more source

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source