Results 171 to 180 of about 189,919 (333)

Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Group‐specific component protein (GC) promotes perineural invasion (PNI) in pancreatic ductal adenocarcinoma (PDAC) by activating Schwann cell dedifferentiation and by enhancing tumor–Schwann cell chemoattraction, independently of vitamin D transport. Integrin β1 (ITGB1) functions as a GC receptor in both cancer cells and Schwann cells.
Shan Zhang, Luju Jiang, Shuqi Cai, Zheqi Weng, Yuheng Zhu, Zhi‐Wei Cai, Hui Li, Qing Li, Li‐Peng Hu, Hong‐Fei Yao, Rong Hua, Yu Zhao, Dongxue Li, Xiao‐Mei Yang, Jun‐Feng Zhang, Shu‐Heng Jiang   +15 more
wiley   +1 more source

Neurotrophic Effects of Epidermal Growth Factor on Cultured Brain Neurons Are Blocked by Protein Kinase Inhibitors

, 1992
Kazuho Abe, Megumi Takayanagi, Hiroshi Saitō   +2 more
openalex   +1 more source

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino, Marco Calabrò, Carmenrita Infortuna, Maria Rosaria Anna Muscatello, Silvana Briuglia, Nicola Cicero, Chiara Fabbri, Alessandro Serretti, Concetta Crisafulli   +8 more
wiley   +1 more source

Purification and Characterization of Neurotrophic Factor for Retinal Cholinergic Neurons Derived from Cultured Hippocampal Neurons.

, 1994
Tohru Yasukura, Kyoko Omori, Toshiko Mikami, Masafumi Inoue, M Uyama, Chiyoko Inagaki   +5 more
openalex   +1 more source

Selective failure of brain-derived neurotrophic factor mRNA expression in the cerebellum of stargazer, a mutant mouse with ataxia [PDF]

, 1996
Xiaoxi Qiao, Franz Hefti, Beat Knüsel, Jeffrey L. Noebels   +3 more
openalex   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

Neurotrophic Factors in Experimental Cerebral Acanthamoebiasis. [PDF]

Int J Mol Sci, 2022
Łanocha-Arendarczyk N, Kot K, Baranowska-Bosiacka I, Kapczuk P, Łanocha A, Kosik-Bogacka DI.   +5 more
europepmc   +1 more source

Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3.

, 1991
Beat Knüsel, John Winslow, Arnon Rosenthal, Louis E. Burton, Derice P. Seid, Károly Nikolics, Franz Hefti   +6 more
openalex   +1 more source

Regulation of Synaptic Function by Neurotrophic Factors in Vertebrates and Invertebrates: Implications for Development and Learning [PDF]

, 1999
Sharen E. McKay, Angela L. Purcell, Thomas Carew   +2 more
openalex   +1 more source

Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé, Lucía García‐DeLaFuente, Alejandro García‐Álvarez, Ginesa García‐Rostán, Jaume Capdevila, Jorge Hernando   +5 more
wiley   +1 more source