Results 121 to 130 of about 1,885 (233)

Motoneuron-Derived Neurotrophin-3 Is a Survival Factor for PAX2-Expressing Spinal Interneurons [PDF]

open access: bronze, 2002
Catherine Béchade   +4 more
openalex   +1 more source

The transcriptomic signature of DEPDC5 KO induced mTOR hyperactivation in human neurons and its response to rapamycin treatment

open access: yesEpilepsia, EarlyView.
Abstract Objective Mutations of the DEP Domain Containing 5 gene (DEPDC5), a mechanistic Target of Rapamycin (mTOR) inhibitor involved in amino acid sensing, are associated with neurological diseases such as epilepsy and/or autism spectrum disorder (ASD). Loss of DEPDC5 impacts early neuronal development via mTOR hyperactivity.
Mattson S. O. Jones   +14 more
wiley   +1 more source

Exploring the roles of conserved context‐dependent cis‐regulatory elements (cdCREs) in multicellularity, human health and disease

open access: yesThe FEBS Journal, EarlyView.
Conserved context‐dependent cis‐regulatory elements act as a major reservoir of disease‐associated polymorphisms in the human genome and are also affected by epigenetic change. This ‘state‐of‐the‐art’ review explores the latest developments in studying these enigmatic elements and how the effects of disease‐associated polymorphisms and environmentally ...
Andrew McEwan   +5 more
wiley   +1 more source

Bacterial porphyrins in healthy skin: Microbiota components impact melanogenesis and age‐related processes leading to Porphyr'ageing

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier   +9 more
wiley   +1 more source

Calcium currents in dissociated cochlear neurons from the chick embryo and their modification by neurotrophin-3

open access: hybrid, 1997
C Jiménez   +3 more
openalex   +1 more source

Chronic Neurotrophin-3 Strengthens Synaptic Connections to Motoneurons in the Neonatal Rat [PDF]

open access: bronze, 2003
Victor L. Arvanian   +3 more
openalex   +1 more source

Histamine-neurotrophin-3 interactions in cultured rat astrocytes [PDF]

open access: yesBMC Pharmacology, 2009
Damijana Mojca Jurič   +2 more
openaire   +2 more sources

Effects of Psychosocial Interventions on Loneliness Amongst Long‐Term Care Residents: A Systematic Review and Meta‐Analysis

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Background Loneliness significantly affects the physical and mental health of older adults, particularly those in long‐term care settings. Despite the high prevalence of loneliness, comprehensive reviews on psychosocial interventions targeting loneliness in these populations are scarce.
Jodie Cheuk‐Yan Szeto   +4 more
wiley   +1 more source

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