Results 121 to 130 of about 1,885 (233)
Motoneuron-Derived Neurotrophin-3 Is a Survival Factor for PAX2-Expressing Spinal Interneurons [PDF]
Catherine Béchade+4 more
openalex +1 more source
Abstract Objective Mutations of the DEP Domain Containing 5 gene (DEPDC5), a mechanistic Target of Rapamycin (mTOR) inhibitor involved in amino acid sensing, are associated with neurological diseases such as epilepsy and/or autism spectrum disorder (ASD). Loss of DEPDC5 impacts early neuronal development via mTOR hyperactivity.
Mattson S. O. Jones+14 more
wiley +1 more source
Conserved context‐dependent cis‐regulatory elements act as a major reservoir of disease‐associated polymorphisms in the human genome and are also affected by epigenetic change. This ‘state‐of‐the‐art’ review explores the latest developments in studying these enigmatic elements and how the effects of disease‐associated polymorphisms and environmentally ...
Andrew McEwan+5 more
wiley +1 more source
753. Neurotrophin-3 Expressed In Situ Induces Axonal Regeneration in the Injured Spinal Cord [PDF]
openalex +1 more source
Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier+9 more
wiley +1 more source
Chronic Neurotrophin-3 Strengthens Synaptic Connections to Motoneurons in the Neonatal Rat [PDF]
Victor L. Arvanian+3 more
openalex +1 more source
Histamine-neurotrophin-3 interactions in cultured rat astrocytes [PDF]
Damijana Mojca Jurič+2 more
openaire +2 more sources
ABSTRACT Background Loneliness significantly affects the physical and mental health of older adults, particularly those in long‐term care settings. Despite the high prevalence of loneliness, comprehensive reviews on psychosocial interventions targeting loneliness in these populations are scarce.
Jodie Cheuk‐Yan Szeto+4 more
wiley +1 more source
Growth arrest of PC12 cells by nerve growth factor is dependent on the phosphatidylinositol 3‐kinase/Akt pathway via p75 neurotrophin receptor [PDF]
Hisanori Ito+2 more
openalex +1 more source