Results 171 to 180 of about 1,885 (233)

Tumor‐Associated Sympathetic Nerves Promote the Progression of Epstein‐Barr Virus‐Positive Diffuse Large B‐Cell Lymphoma

Advanced Science, Volume 12, Issue 33, September 4, 2025.
Sympathetic nerve innervation promotes the progression of Epstein‐Barr virus‐positive diffuse large B‐cell lymphoma (EBV+ DLBCL) via β2‐adrenergic receptors. The discovery of enhanced nerve infiltration and β2AR expression reveals a novel mechanism and highlights the sympathetic–β2AR axis as a promising target for therapeutic intervention in EBV+ DLBCL.
Silan Huang, Dexin Lei, Linbin Yang, Aiwei Bi, Yanlou Wang, Peng Zhang, Dongyu Zhuang, Honglian Liu, Qingqing Cai, Man Nie, Yi Xia   +10 more
wiley   +1 more source

Diabetic Schwann cells suffer from nerve growth factor and neurotrophin-3 underproduction and poor associability with axons [PDF]

, 2013
Indranil Dey, Nisha Midha, Geeta S. Singh, Amanda Forsyth, Sarah K. Walsh, Bhagat Singh, Ranjan Kumar, Cory Toth, Rajiv Midha   +8 more
openalex   +1 more source

The Longitudinal Association Between Chronic Back Pain and Cognitive Decline in Older Adults With Mediation Analysis: An Analysis of Four Population‐Based Databases

European Journal of Pain, Volume 29, Issue 8, September 2025.
ABSTRACT Background While studies suggest chronic back pain (CBP) may heighten accelerated cognitive decline risk in older adults, no multinational research has comprehensively examined this significant public health concern alongside healthy lifestyles' potential impact. Methods Data from 18,558 individuals across 17 countries (China, England, Europe,
Frank F. Huang, Yuying Zhang, Lian Liu, Chun Liang Hsu, Raymond Chung, Wanming Wu, Daniel K. Y. Zheng, Zihui Xiong, Jeremy R. Chang, Yongping Zheng, Manuela L. Ferreira, Paulo H. Ferreira, F. U. Amy, Fadi A. L. Zoubi, Hio Teng Leong, Arnold Y. L. Wong   +15 more
wiley   +1 more source

Neurobiological Synergy of Plant and Animal Sources of Omega‐3 and Exercise in Aging: Implications for Molecular Signaling, Memory, Spatial Learning, and Brain Function

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
Omega‐3 fatty acids from animal sources, combined with exercise, modulate key molecular pathways to enhance neurogenesis, synaptic plasticity, and antioxidant defenses. These interventions also increase tissue plasminogen activator activity, promoting both amyloid‐β degradation and proBDNF cleavage into BDNF, thereby reducing neurodegeneration and ...
Yikuang Hao, Sima‐sadat Sabihi
wiley   +1 more source

Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice

Glia, Volume 73, Issue 9, Page 1817-1840, September 2025.
Main Point Spatial transcriptomic analysis unravels the mechanisms by which HDACi ameliorates neuroinflammation and enhances neuroprotection by modulating the expression of microglial transcriptomes in the ischemic mouse brain. ABSTRACT Ischemic stroke significantly contributes to global morbidity and disability through a cascade of neurological ...
Kevin Jayaraj, Ritesh Kumar, Sukanya Shyamasundar, Thiruma V. Arumugam, Jai S. Polepalli, S. Thameem Dheen   +5 more
wiley   +1 more source

Unmasking of Spiral Ganglion Neuron Firing Dynamics by Membrane Potential and Neurotrophin-3 [PDF]

, 2014
Robert A. Crozier, Robin L. Davis
openalex   +1 more source

A Conceptual Review of Naturally Occurring Toxins and Venoms as Peptide Blockers to Combat Chronic Low Back Pain

JOR SPINE, Volume 8, Issue 3, September 2025.
This review explores the therapeutic potential of naturally occurring venom‐derived peptides, particularly from reptiles and insects, as novel calcium channel blockers for managing chronic low back pain caused by intervertebral disc degeneration.
James Melrose, Stone Sima, Neha Chopra, Ashish Diwan, Zi Gu   +4 more
wiley   +1 more source

Immunohistochemical detection of neurotrophin-3 and -4, and their receptors in mouse taste bud cells

, 2005
Masako Takeda, Yuko Suzuki, Nobuko Obara, Hiroaki Tsunekawa   +3 more
openalex   +2 more sources

Balance and coordination training, but not endurance training, enhances synaptophysin and neurotrophin‐3 immunoreactivity in the lumbar spinal cord after sciatic nerve crush [PDF]

, 2015
Leandro Viçosa Bonetti, Jocemar Ilha, Ana Paula Krauthein Schneider, Sílvia Barbosa, Maria Cristina Faccioni‐Heuser   +4 more
openalex   +1 more source

Spatiotemporal Dynamics of Central Nervous System Diseases: Advancing Translational Neuropathology via Single‐Cell and Spatial Multiomics

MedComm, Volume 6, Issue 9, September 2025.
Central nervous system (CNS) diseases are driven by spatiotemporally dynamic molecular networks. Single‐cell and spatial multiomics technologies dissect cellular heterogeneity, microenvironmental remodeling, and intercellular crosstalk. Integration of transcriptomic, epigenomic, proteomic, and metabolomic layers reveals disease‐associated regulatory ...
Mingkai Xia, Quan Liu, Wenli Zhang, Jinwen Ge, Zhigang Mei   +4 more
wiley   +1 more source