Results 11 to 20 of about 1,885 (233)
Current Issues in Molecular Biology, 2023 Microglial cells play an important role in neuroinflammation and secondary damages after spinal cord injury (SCI). Progressive microglia/macrophage inflammation along the entire spinal axis follows SCI, and various factors may determine the microglial ...
Diana Schaufler +4 more
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Neuroprotective effects of Neurotrophin-3 in MPTP-induced zebrafish Parkinson’s disease model
Frontiers in Pharmacology, 2023 Introduction: Neurotrophin-3 (NT3) is a neuroprotective growth factor that induces the development, maintenance and survival of neurons. This study aims to localize NT3-expressing cells in the adult zebrafish brain and examine the role of NT3 in a ...
Noor Azzizah Omar +3 more
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Local Effect of Neurotrophin-3 in Neuronal Inflammation of Allergic Rhinitis: Preliminary Report
Balkan Medical Journal, 2015 Background: Allergic rhinitis is a common inflammatory nasal mucosal disease characterized by sneezing, watery nasal discharge, nasal obstruction and itching.
Onur İsmi +6 more
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Brain Sciences, 2021 Type 2 diabetes mellitus (T2DM) is known to be associated with an increased risk of dementia, specifically Alzheimer’s disease and vascular dementia. Intermittent fasting (IF) has been proposed to produce neuroprotective effects through the activation of
Basem H. Elesawy +4 more
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Neurotrophin-3 signals redistribute RNA in neurons [PDF]
Proceedings of the National Academy of Sciences, 1997 The translocation of specific mRNAs to dendrites and their potential for locally regulated translation are likely to serve as an effector in neuronal plasticity. Whether translation in dendrites is regulated by delivery of the RNA to sites of plasticity or a stationary pool of localized RNA undergoes enhanced translational efficiency is not clear.
Kenneth S. Kosik, Roger B. Knowles
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Endogenous neurotrophin-3 promotes neuronal sprouting from dorsal root ganglia
Neural Regeneration Research, 2015 In the present study, we investigated the role of endogenous neurotrophin-3 in nerve terminal sprouting 2 months after spinal cord dorsal root rhizotomy.
Xu-yang Wang +8 more
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Neurotrophin-3 Involvement in the Regulation of Hair Follicle Morphogenesis [PDF]
Journal of Investigative Dermatology, 1998 Hair follicle epithelium and nervous system share a common ectodermal origin, and some neurotrophins can modulate keratinocyte proliferation and apoptosis. It is therefore reasonable to ask whether growth factors that control neural development are also involved in the regulation of hair follicle morphogenesis. Focusing on neurotrophin-3 (NT-3) and its
Ralf Paus +5 more
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Clinics, 2006 OBJECTIVE: For many years, it was believed that medullary regeneration could not occur, although currently there are many trials using neurotrophic factors, stem cells, fetal medulla grafts, peripheral nerve grafts, and antibodies against myelin ...
Douglas Kenji Narazaki +6 more
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Biology, 2020 The failure of the spinal cord to regenerate can be attributed both to a lack of trophic support for regenerating axons and to upregulation of inhibitory factors such as chondroitin sulphate proteoglycans including NG2 following injury. Lentiviral vector-
Azim Patar +3 more
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eLife, 2016 Brain and spinal injury reduce mobility and often impair sensorimotor processing in the spinal cord leading to spasticity. Here, we establish that complete transection of corticospinal pathways in the pyramids impairs locomotion and leads to increased ...
Claudia Kathe +3 more
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