Results 41 to 50 of about 16,647,982 (293)
The Many Hats of Sonic Hedgehog Signaling in Nervous System Development and Disease. [PDF]
, 2016 Sonic hedgehog (Shh) signaling occurs concurrently with the many processes that constitute nervous system development. Although Shh is mostly known for its proliferative and morphogenic action through its effects on neural stem cells and progenitors, it ...
Belgacem, Yesser H +4 more
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Muscle Progenitors Derived from Extraocular Muscles Express Higher Levels of Neurotrophins and their Receptors than other Cranial and Limb Muscles [PDF]
, 2020 Extraocular muscles (EOMs) show resistance to muscle dystrophies and sarcopenia. It has been recently demonstrated that they are endowed with different types of myogenic cells, all of which present an outstanding regenerative potential. Neurotrophins are
Benítez Temiño, Beatriz +3 more
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Production and characterization of recombinant mouse neurotrophin‐3 [PDF]
European Journal of Biochemistry, 1992 Neurotrophin‐3 (NT‐3) is a neurotrophic factor that has recently been cloned on the basis of its structural similarity to other members of the nerve growth factor (NGF) gene family. In order to produce this protein, a recombinant vaccinia virus containing the coding region for mouse NT‐3 was constructed. Conditioned medium harvested from cells infected
Gotz, R. +3 more
openaire +2 more sources
The gut-brain axis, BDNF, NMDA and CNS disorders [PDF]
, 2016 Gastro-intestinal (GI) microbiota and the ‘gut-brain axis’ are proving to be increasingly relevant to early brain development and the emergence of psychiatric disorders.
Maqsood, Raeesah, Stone, Trevor W.
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High abundances of neurotrophin 3 in atopic dermatitis mast cell
Journal of Occupational Medicine and Toxicology, 2009 Background Neurotrophin 3 (NT-3) is a member of the neurotrophin family, a group of related proteins that are known to regulate neuro-immune interactions in allergic diseases.
Groneberg David A +4 more
doaj +1 more source
eLife, 2014 Neurotrophin-3 (Ntf3) and brain derived neurotrophic factor (Bdnf) are critical for sensory neuron survival and establishment of neuronal projections to sensory epithelia in the embryonic inner ear, but their postnatal functions remain poorly understood.
Guoqiang Wan +4 more
semanticscholar +1 more source
PLG Bridge Implantation in Chronic SCI Promotes Axonal Elongation and Myelination. [PDF]
, 2019 Spinal cord injury (SCI) is a devastating condition that may cause permanent functional loss below the level of injury, including paralysis and loss of bladder, bowel, and sexual function.
Anderson, Aileen J +8 more
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Neurotrophin-3 improves fracture healing in rats.
European review for medical and pharmacological sciences, 2018 This study aimed at investigating the role of Neurotrophin-3 (NT-3) in the bone fracture healing of rats and to provide a reference for clinical treatment.40 Sprague-Dawley (SD) rats were randomly divided into control group and NT-3 group. The tibia fracture model was made in NT-3 group, and the tibia bone mineral density (BMD) was measured before and ...
Li, X., Sun, D.-C., Li, Y., Wu, X.-Y.
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Introduction of a Neurotrophin-3 Transgene into Muscle Selectively Rescues Proprioceptive Neurons in Mice Lacking Endogenous Neurotrophin-3 [PDF]
Neuron, 1997 To clarify the role of muscle-derived neurotrophin-3 (NT-3) in the development of sensory neurons, we generated transgenic mice selectively overexpressing NT-3 in skeletal muscles under the control of a myogenin promoter (myo-NT-3 mice). The myo-NT-3 transgene was then bred into an NT-3 null mutant (-/-) line to generate myo-NT-3, NT-3(-/-) mice in ...
Wright, D.E +3 more
openaire +2 more sources
Molecular Therapy, 2014 Neural stem cells (NSCs) have therapeutic potential in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS); however, to date, their use has resulted in only limited clinical and pathological improvement. To enhance
Jingxian Yang +8 more
semanticscholar +1 more source