Results 81 to 90 of about 1,885 (233)
Frontiers in Psychiatry, 2012 Background: There is increasing evidence that glial cells play a role in the pathomechanisms of mood disorders and the mode of action of antidepressant drugs.
Sarah eKittel-Schneider +9 more
doaj +1 more source
Investigating the mechanisms of capsicum in age‐related hearing loss: Based on network pharmacology
Eye &ENT Research, EarlyView.Abstract Background To explore the material basis and action mechanism of the chemical component gene of pepper on presbycusis, and to provide a reference for the traditional Chinese medicine treatment of age‐related hearing loss (ARHL). Methods The chemical composition and action targets of traditional Chinese medicine flavor of pepper were searched ...
Yan Wang +9 more
wiley +1 more source
Glia, EarlyView.AAV‐BDNF improves cognitive performance after cuprizone‐induced de‐myelination. BDNF promotes OPC maturation and enhances remyelination in the corpus callosum. Mitochondrial integrity is preserved through reduced swelling and improved morphology. ABSTRACT Multiple sclerosis (MS) is a chronic neurological disorder involving immune‐mediated demyelination
Yousra El Ouaamari +14 more
wiley +1 more source
The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance
Glia, EarlyView.Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons during rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic lipids and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production of ...
Rose Follis +2 more
wiley +1 more source
Neurobiology of Disease, 1998 In the present study we have evaluated changes in nerve growth factor (NGF), brain-derived neurotrophic factor, and neurotrophin 3 (NT-3) mRNA expression induced by different glutamate receptor agonists injected into the neostriatum. Up-regulation of NGF
Josep M. Canals +6 more
doaj +1 more source
Glia Preserve Their Own Functions While Compensating for Neighboring Glial Cell Dysfunction
Glia, EarlyView.When cortex glia lose their interactions with neuronal cell bodies, all neighboring glia infiltrate the region to clear extra neuronal corpses. Even while compensating for nearby glial dysfunction, glia maintain their own phagocytic functions. ABSTRACT Glial cells are essential for nervous system development, homeostasis, and disease response, engaging
Allison N. Beachum +13 more
wiley +1 more source
Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: interactions with amphetamine [PDF]
, 1994 Mathew T. Martin‐Iverson +2 more
openalex +1 more source
Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells
Frontiers in Immunology, 2017 Plasmacytoid dendritic cells (pDCs) regulate innate and adaptive immunity. Neurotrophins and their receptors control the function of neuronal tissue. In addition, they have been demonstrated to be part of the immune response but little is known about the
Joanna Bandoła +19 more
doaj +1 more source
Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis
Glia, EarlyView.OECs are similar to satellite glial cells. OECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. OECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs) envelope ...
Katja Senf +3 more
wiley +1 more source
Purification and characterisation of a brain‐derived neurotrophic factor/ neurotrophin‐3 (BDNF/NT‐3) heterodimer [PDF]
, 1994 Stefan Jungbluth +2 more
openalex +1 more source