The High‐Intensity Zone: A Dynamic Inflammatory Hub in Lumbar Disc Degeneration
The HIZ, a dynamic inflammatory hub in lumbar disc degeneration, links inflammation‐degeneration‐pain; integrating advanced diagnostics and targeted therapies offers precise management for discogenic low back pain. ABSTRACT The lumbar intervertebral disc high‐intensity zone (HIZ), a focal hyperintensity within the annulus fibrosus on T2‐weighted ...
Qi Zhou +6 more
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Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti +6 more
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Abstract figure legend Schematic overview of the 5 day lower‐limb motor skill learning protocol combining ankle visuomotor practice with transcranial direct current stimulation (tDCS). Participants were allocated to motor skill practice with active tDCS over the leg representation of primary motor cortex (SKILL‐STIM), motor skill practice with sham ...
August Lomholt Kvistad +5 more
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Neurotrophins and Psychiatric Disorders
Increasing number of studies has during the last decade linked neurotrophic factors with the pathophysiology of neuropsychiatric disorders and with the mechanisms of action of drugs used for the treatment of these disorders. In particular, brain-derived neurotrophic factor BDNF and its receptor TrkB have been connected with the pathophysiology in mood ...
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Comparison of BDNF and NGF Levels in Adenomyotic Tissue, Adjacent Myometrium, and Normal Myometrium and Their Correlation with Pain Severity. [PDF]
Heriyanto A +7 more
europepmc +1 more source
Molecular neurobiological insights on integrative role of Trk neurotrophic receptors and their small-molecule agonists in neurodegenerative conditions. [PDF]
Sanjai M +5 more
europepmc +1 more source
A Review of the Clinical Applicability of Neurotrophins in Cochlear Implantation. [PDF]
Ahn SC.
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Epigenetic Regulation of Trk Receptors and Neurotrophic Signalling in Neuroblastoma: Mechanisms, Plasticity, and Therapeutic Opportunities. [PDF]
Siddi C, Balla J, Fadda P, Dedoni S.
europepmc +1 more source
Impact of Chronic Mild Stress on Neurotrophic and Hypothalamic-Pituitary-Adrenal Factors in the Brain of Rats Submitted to Sepsis. [PDF]
Peper-Nascimento J +7 more
europepmc +1 more source
Citation: 'neurotrophin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11014 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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