Results 81 to 90 of about 35,168 (213)

From Neural Crest Development to Cancer and Vice Versa: How p75NTR and (Pro)neurotrophins Could Act on Cell Migration and Invasion?

open access: yesFrontiers in Molecular Neuroscience, 2018
The p75 neurotrophin receptor (p75NTR), also known as low-affinity nerve growth factor, belongs to the tumor necrosis factor family of receptors. p75NTR is widely expressed in the nervous system during the development, as well as, in the neural crest ...
Sabine Wislet   +3 more
doaj   +1 more source

Clinical Relevance of Lymphovascular and Perineural Invasion in Oral Squamous Cell Carcinoma: Emphasis on Pathological N1 Cases

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective This study aimed to investigate the clinical relevance of lymphovascular invasion (LVI) and perineural invasion (PNI) in oral squamous cell carcinoma (OSCC). Methods We conducted a retrospective study of 181 OSCC patients, analyzing clinical outcomes in terms of disease‐specific survival (DSS) and disease‐free survival (DFS ...
Juan Carlos de Vicente   +8 more
wiley   +1 more source

Through the Sands of Time: Evolutionary History and Systematics of the Awl‐Headed Snakes (Colubridae: Lytorhynchus) in the Saharo‐Sindian Region

open access: yesZoologica Scripta, EarlyView.
ABSTRACT The psammophilous colubrid genus Lytorhynchus is widely distributed in the deserts of the Saharo‐Sindian region and adjacent areas. The taxonomy of the genus and the number of recognised species have remained unstable since the last taxonomic revision in 1970, with differing views on the taxonomic status of L. gaddi and L. kennedyi.
Lukáš Pola   +10 more
wiley   +1 more source

Eight weeks of post‐exercise local heating does not improve cognition and plasma brain‐derived neurotrophic factor concentrations

open access: yesExperimental Physiology, EarlyView.
Abstract Exercise and heat stress have been reported to independently provide benefits to brain health. We tested the hypothesis that 8 weeks of post‐exercise local heating, passive local heating only, or exercise training only improves cognitive performance compared to a control group.
Jem L. Cheng   +6 more
wiley   +1 more source

Maternal obesity during lactation as a hypertensive cardiovascular risk factor in the offspring

open access: yesExperimental Physiology, EarlyView.
Abstract Maternal obesity is a major public health concern, with growing evidence supporting its role in the developmental programming of cardiometabolic disease. Although prenatal mechanisms have been investigated extensively, the contribution of lactation as a postnatal window of cardiovascular (CV) programming remains insufficiently understood ...
Gabriela Arenas   +2 more
wiley   +1 more source

Acute and lifelong exercise modulate the tumorigenic potential of human lung cancer cells and their susceptibility to cisplatin

open access: yesExperimental Physiology, EarlyView.
Abstract The association between higher levels of physical activity and lower cancer risk and mortality is well established. However, a causal link is yet to be proven. Recent studies showed a decrease in the proliferation rates of cultured human cancer cells when the human serum used to stimulate them was conditioned by acute exercise. Here, we tested
Carlos M. Soares   +7 more
wiley   +1 more source

Arterial–venous differences of brain‐derived neurotrophic factor isoforms across the brain and muscle after exercise at different intensities

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Exercise‐induced increases in forearm venous plasma and serum brain‐derived neurotrophic factor (BDNF) are often assumed to be indicative of release from the brain. Sixteen healthy and physically fit adults (20–40 years old) were recruited to investigate whether exercise‐induced changes in forearm venous mature BDNF (mBDNF) and ...
Olga Tarassova   +10 more
wiley   +1 more source

Optimizing transport methods to preserve function of self‐innervating muscle cells for laryngeal injection

open access: yesLaryngoscope Investigative Otolaryngology
Objectives Recently, our laboratory has discovered a self‐innervating population of muscle cells, called motor endplate‐expressing cells (MEEs). The cells innately release a wide variety of neurotrophic factors into the microenvironment promoting ...
Samuel L. Kaefer   +5 more
doaj   +1 more source

The relationship between psychological distress and neurotrophins in patients with alopecia areata: A crosssectional study

open access: yesTurkderm Turkish Archives of Dermatology and Venereology
Background and Design: Alopecia areata (AA) is a common, chronic, autoimmune disease that causes psychological effects on patients. Distress and psychological factors play roles in the onset and flares of the disease.
Hatice Parlak Subaşı   +6 more
doaj   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil   +11 more
wiley   +1 more source

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