Results 201 to 210 of about 72,847 (330)

CSF proteomic profiling with amyloid and tau pathology identifies distinctive sex‐specific alteration of multiple proteins involved in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION In Alzheimer's disease (AD), females have higher prevalence and faster progression, but sex‐specific molecular findings in AD are limited. METHODS We comprehensively examined 6162 proteins in cerebrospinal fluid (CSF) from 2496 participants to identify sex‐specific proteomic alteration by CSF amyloid beta (Aβ)42 and phosphorylated
Anh N. Do   +17 more
wiley   +1 more source

Chinese Yam (Dioscorea) Improves Psychiatric Comorbidities of Colitis Mice Through Regulating 5‐HT Metabolism

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
CY alleviates colitis and associated neuropsychiatric symptoms by reducing serum LPS, restoring intestinal barrier integrity, and modulating serotonin metabolism. It inhibits neuroinflammation, improves synaptic function, and normalizes HPA axis hyperactivity via downregulation of HTR2C, offering a multi‐targeted strategy for gut–brain axis dysfunction
Yifan Cui   +9 more
wiley   +1 more source

A Procedural Overview of the Involvement of Small Molecules in the Nervous System in the Regulation of Bone Healing

open access: yesInternational Journal of Nanomedicine
Xuyan Wei,1,2 Mucong Li,1,2 Jiaqian You,1,2 Jiaxin Luo,1,2 Jingjie Zhai,1,2 Jiameng Zhang,1,2 Jian Feng,1,2 Hanchi Wang,1,2 Yanmin Zhou1,2 1Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin ...
Wei X   +8 more
doaj  

Expression of Neurotrophin Genes in the Hypothalamus of Stressed and Allopregnanolone-Infused Sheep. [PDF]

open access: yesInt J Mol Sci
Młotkowska P   +4 more
europepmc   +1 more source

Dihydroquercetin Attenuates Silica‐Induced Pulmonary Fibrosis by Modulating the Gut Microbiota and the Serum Metabolites in Mice

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
(1) DHQ can attenuate silica‐induced inflammation and pulmonary fibrosis in the C57BL/6 mice. (2) The beneficial effects of DHQ were primarily attributed to the alteration of gut microbiota (particularly Muribaculaceae and Lactobacillus) mediated by serum metabolites.
Zunqiong Ke   +5 more
wiley   +1 more source

Targeted Delivery of Microneurotrophin BNN27 via Biomaterial Grafts Protects Retinal Ganglion Cells After Optic Nerve Injury

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 1, January 2026.
ABSTRACT Emerging neurotrophin treatments for optic nerve injury (ONI) aim to prevent the loss of retinal ganglion cells (RGCs) and enhance axonal regeneration. Microneurotrophins (MNTs), small‐molecule mimetics of neurotrophins, have shown neuroprotective effects in various animal models of neurodegeneration, yet MNT effects on ONI remain unknown ...
K. Georgelou   +13 more
wiley   +1 more source

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