Allogeneic Bone Marrow‐Derived Mesenchymal Stem Cells for Parkinson's Disease: A Randomized Trial
Movement Disorders, EarlyView.Abstract Background Neuroinflammation contributes to Parkinson's disease (PD) progression and motor dysfunction. Allogeneic human mesenchymal stem cells (allo‐hMSCs) may reduce neuroinflammation and improve motor symptoms. Objectives To evaluate the efficacy of repeated intravenous doses of 10 × 106/kg allo‐hMSCs in improving motor symptoms in patients
Mya C. Schiess +15 more
wiley +1 more source
Identification of an essential nonneuronal function of neurotrophin 3 in mammalian cardiac development [PDF]
, 1996 Michael J. Donovan +3 more
openalex +1 more source
Molecular Nutrition &Food Research, EarlyView.Paired peripheral‐blood RNA‐seq from MiBLEND was deconvolved with CIBERSORTx to profile leukocyte composition and cell‐type‐specific transcriptomic responses to seven fruit‐and‐vegetable blends. Deconvolution yielded 22 leukocyte subtypes that correlated with laboratory WBC reports (R = 0.886, p ≤ 0.01).
Yueqin He +3 more
wiley +1 more source
Differential expression of neurotrophins in postnatal C57BL/6 mice striatum
International Journal of Biological Sciences, 2009 Neurotrophin expression in early stages of development is crucial for brain assembly and function. In particular, postnatal expression of neurotrophins has not been well documented in the neostriatum and in general neurotrophins or their receptor mRNA's ...
V. Zermeño, S. Espindola, E. Mendoza, E. Hernández-Echeagaray
doaj
Effects of Whole-Body Vibration and Manually Assisted Locomotor Therapy on Neurotrophin-3 Expression and Microglia/Macrophage Mobilization Following Thoracic Spinal Cord Injury in Rats. [PDF]
Curr Issues Mol Biol, 2023 Schaufler D +4 more
europepmc +1 more source
A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
Neuroprotection, EarlyView.This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley +1 more source
Detection and Quantification of Neurotrophin-3 (NT-3) and Nerve Growth Factor (NGF) Levels in Early Second Trimester Amniotic Fluid: Investigation into a Possible Correlation with Abnormal Fetal Growth Velocity Patterns. [PDF]
J Clin Med, 2023 Machairiotis N +14 more
europepmc +1 more source
Sympathetic neurons in neonatal rats require endogenous neurotrophin-3 for survival [PDF]
, 1995 Xin‐Fu Zhou, Ryan B. Rush
openalex +1 more source
Neuroprotection, EarlyView.Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal +2 more
wiley +1 more source
Serum Levels of Growth-Associated Protein-43 and Neurotrophin-3 in Childhood Epilepsy and Their Relation to Zinc Levels. [PDF]
Biol Trace Elem Res, 2023 Bakri AH +6 more
europepmc +1 more source