Results 191 to 200 of about 58,898 (268)

The Association Between Irritable Bowel Syndrome and Generalized Anxiety Disorder and Influencing Factors: A Mediation Mendelian Randomization Study

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Based on Mendelian randomization analysis, this study established a significant causal effect of irritable bowel syndrome (IBS) on increasing generalized anxiety disorder (GAD) risk (odds ratio = 1.328; p < 0.001) and identified dozens of gut microbial taxa, plasma metabolites, inflammatory factors, and immune cell characteristics with potential causal
Weili Yang, Yongxi Wang, Shasha Wang, Hongbing Zhai, Jun Che, Xin Wang, Yafeng Yang, Zebo Jia   +7 more
wiley   +1 more source

Effects of cholecalciferol supplementation on depressive symptoms, C-peptide, serotonin, and neurotrophin-3 in type 2 diabetes mellitus: A double-blind, randomized, placebo-controlled trial. [PDF]

Narra J
Putranto R, Setiati S, Nasrun MW, Witjaksono F, Immanuel S, Subekti I, Harimurti K, Siswanto A, Shatri H, Suwarto S, Megantara MA.   +10 more
europepmc   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

From hidden hearing loss to supranormal auditory processing by neurotrophin 3-mediated modulation of inner hair cell synapse density. [PDF]

PLoS Biol
Ji L, Borges BC, Martel DT, Wu C, Liberman MC, Shore SE, Corfas G.   +6 more
europepmc   +1 more source

Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies

MedComm, Volume 7, Issue 2, February 2026.
The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu, Zhi‐Shan Ge, Qing‐Yue Cao, Zi‐Han Li, An Zhang, Hai‐Dong Zhu, Gao‐Jun Teng   +6 more
wiley   +1 more source

Electroacupuncture facilitates the integration of a grafted TrkC-modified mesenchymal stem cell-derived neural network into transected spinal cord in rats via increasing neurotrophin-3. [PDF]

CNS Neurosci Ther, 2021
Yang Y, Xu HY, Deng QW, Wu GH, Zeng X, Jin H, Wang LJ, Lai BQ, Li G, Ma YH, Jiang B, Ruan JW, Wang YQ, Ding Y, Zeng YS.   +14 more
europepmc   +1 more source

Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin‐1 Loss

Aging Cell, Volume 25, Issue 2, February 2026.
Senescent hippocampal astrocytes lose TSP secretion, impairing excitatory synaptogenesis via the α2δ‐1 pathway. Restoring TSP‐1 rescues synaptic formation, revealing the contribution of astrocyte senescence to age‐related hippocampal synaptic decline.
Stefano Ercoli, Lucía Casares‐Crespo, Elena Juárez‐Escoto, Helena Mira   +3 more
wiley   +1 more source

Eurycomanone from Eurycoma longifolia Jack upregulates neurotrophin-3 gene expression in retinal Müller cells in vitro. [PDF]

J Clin Biochem Nutr
Sakai Y, Yamada M, Watanabe T, Yamazaki A, Furukawa M, Izumo N, Matsuzaki H.   +6 more
europepmc   +1 more source

Controlling the Release of Neurotrophin-3 and Chondroitinase ABC Enhances the Efficacy of Nerve Guidance Conduits. [PDF]

Adv Healthc Mater, 2020
Donsante A, Xue J, Poth KM, Hardcastle NS, Diniz B, O'Connor DM, Xia Y, Boulis NM.   +7 more
europepmc   +1 more source

Can Environmental Enrichment Mitigate Cell Apoptosis in the Central Nervous System Under Adverse Health Conditions? A Systematic Review

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT To summarize the available evidence in the literature regarding the effects of exposure to an enriched environment (EE) on the modulation of apoptotic markers in central tissue of rodents under unfavorable conditions. Searches were conducted in three databases: PubMed/Medline (70 articles), Scopus (65 articles), and EMBASE (128 articles), all ...
Matheus Santos de Sousa Fernandes, Diorginis José Soares Ferreira, Fatma Hilal Yagin, Georgian Badicu, Gabriela Carvalho Jurema Santos, Maria Carolina Santos Guedes, Fabrício Oliveira Souto, Luca Paolo Ardigò   +7 more
wiley   +1 more source