Results 231 to 240 of about 58,898 (268)
Some of the next articles are maybe not open access.
Biochemistry, 1994
The neurotrophins are a family of small dimeric proteins required for the development and survival of vertebrate neurons. Solvent denaturation studies were used to compare recombinant human nerve growth factor (hNGF), brain-derived neurotrophic factor (BDNF), neurotrophin 3 (NT-3), and neurotrophin 4/5 (NT-4/5) to nerve growth factor isolated from ...
D E, Timm, P L, de Haseth, K E, Neet
openaire +2 more sources
The neurotrophins are a family of small dimeric proteins required for the development and survival of vertebrate neurons. Solvent denaturation studies were used to compare recombinant human nerve growth factor (hNGF), brain-derived neurotrophic factor (BDNF), neurotrophin 3 (NT-3), and neurotrophin 4/5 (NT-4/5) to nerve growth factor isolated from ...
D E, Timm, P L, de Haseth, K E, Neet
openaire +2 more sources
European Journal of Pharmacology, 1995
Neurotrophins and growth factors not only affect neuronal development, but also maintain neuronal survival and influence neuronal function in the adult brain, and affect various cognitive processes related to learning and memory. Functional tolerance to ethanol represents an adaptive change in the central nervous system that has been hypothesized to ...
G, Szabò, P L, Hoffman
openaire +2 more sources
Neurotrophins and growth factors not only affect neuronal development, but also maintain neuronal survival and influence neuronal function in the adult brain, and affect various cognitive processes related to learning and memory. Functional tolerance to ethanol represents an adaptive change in the central nervous system that has been hypothesized to ...
G, Szabò, P L, Hoffman
openaire +2 more sources
International Journal of Developmental Neuroscience, 1994
AbstractHippocampal levels of mRNA encoding nerve growth factor (NGF) and brain‐derived neurotrophic factor (BDNF) are rapidly induced by enhanced neuronal activity following seizures and glutamate or muscarinic receptor activation. However, the levels of neurotrophin‐3 (NT‐3) mRNA acutely decrease after limbic seizures suggesting that a different mode
D, Lindholm +4 more
openaire +2 more sources
AbstractHippocampal levels of mRNA encoding nerve growth factor (NGF) and brain‐derived neurotrophic factor (BDNF) are rapidly induced by enhanced neuronal activity following seizures and glutamate or muscarinic receptor activation. However, the levels of neurotrophin‐3 (NT‐3) mRNA acutely decrease after limbic seizures suggesting that a different mode
D, Lindholm +4 more
openaire +2 more sources
Apoptosis of Merkel cells in neurotrophin-3 null mice
Anatomy and Embryology, 2005Postnatal mice lacking neurotrophin-3 (NT3) are deficient in Merkel cells of touch domes and whisker follicles. We examined the mechanism of Merkel cell loss by immunocytochemistry and electron microscopy. Merkel cell of whisker follicles of NT3 null newborns exhibited decreased immunoreactivity for cytokeratin 8 and contained apoptotic bodies that ...
Zdenek, Halata +3 more
openaire +2 more sources
Dependence of developing group Ia afferents on neurotrophin‐3
Journal of Comparative Neurology, 1995AbstractAt birth, group Ia proprioceptive afferents and muscle spindles, whose formation is Ia afferent‐dependent, are absent in mice carrying a deletion in the gene for neurotrophin‐3 (NT‐3 –/–). Whether Ia afferents contact myotubes, resulting in the formation of spindles which subsequently degenerate, or whether Ia afferents and spindles never form ...
J, Kucera +4 more
openaire +2 more sources
Decreased serum neurotrophin 3 in chronically medicated schizophrenic males
Neuroscience Letters, 2008There is evidence that major psychiatric disorders such as schizophrenia (SZ) are associated with deregulation of synaptic plasticity with downstream alterations of neurotrophins. NT3 is an important neurotrophin in the central nervous system, and performs key biological functions, such as promoting the survival, differentiation, and plasticity of ...
Vargas, Haroldo Evangelista +10 more
openaire +3 more sources
Investigation of neuromuscular abnormalities in neurotrophin‐3‐deficient mice
European Journal of Neuroscience, 2009AbstractNeurotrophin‐3 (NT‐3) is a trophic factor that is essential for the normal development and maintenance of proprioceptive sensory neurons and is widely implicated as an important modulator of synaptic function and development. We have previously found that animals lacking NT‐3 have a number of structural abnormalities in peripheral nerves and ...
Philip W, Sheard +6 more
openaire +2 more sources
Neurotrophin–3 knocks heart off Trk
Nature Medicine, 1996D, Srivastava, E N, Olson
openaire +2 more sources
Neurotrophin-3 gene and schizophrenia
Schizophrenia Research, 1995S. Nanko, M. Hattori, H. Kazamatsuri
openaire +1 more source