Results 161 to 170 of about 44,486 (289)

p75 neurotrophin receptor as a modulator of survival and death decisions [PDF]

open access: bronze, 1999
Patrizia Casaccia‐Bonnefil   +3 more
openalex   +1 more source

Characteristic, Regulation and Targeting Strategies of Cancer Stem Cells and Their Niche in Digestive System Tumors

open access: yesMedComm – Oncology, Volume 4, Issue 2, June 2025.
Cancer stem cells, characterized by self‐renewal, differentiation, heterogeneity, plasticity and tumorigenicity, are regulated by intrinsic factors such as signaling pathways, transcription factors, metabolism and noncoding RNAs, as well as environmental cells (including tumor cells, immune cells and stromal cells), environmental factors and distant ...
Zhenzhen Chen   +11 more
wiley   +1 more source

Combined Neurotoxic Effects of Commercial Formulations of Pyrethroid (Deltamethrin) and Neonicotinoid (Imidacloprid) Pesticides on Adult Zebrafish (Danio rerio): Behavioral, Molecular, and Histopathological Analysis

open access: yesLife
The use of different commercial products that involve one or multiple active substances with specific targeted-pests control has become a widespread practice. Because of this, a severe range of significant consequences has been often reported.
Adriana Petrovici   +4 more
doaj   +1 more source

Antisense oligonucleotides directed against App and Rab5 normalized endosomal Rab activity and reversed DS‐AD‐linked degenerative phenotypes in the Dp16 mouse model of Down syndrome

open access: yesAlzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract INTRODUCTION Down syndrome (DS) markedly raises the risk of Alzheimer's disease (DS‐AD). Our findings identified widespread dysregulation of the endolysosomal network (ELN) in DS and DS‐AD brains, driven by increased APP gene dose, hyperactivation of RAB5, and elevated levels of guanine nucleotide exchange factors (GEFs) for RABs 7 and 11 ...
Xu‐Qiao Chen   +12 more
wiley   +1 more source

The Causal Relationship Between Neurotrophic Factors and Delirium: A Mendelian Randomization Study

open access: yesBrain and Behavior, Volume 15, Issue 5, May 2025.
Overview of MR analysis. SNPs: single nucleotide polymorphisms; inverse‐variance weighted (IVW); weighted median (WM); leave‐one‐out (LOO); glial cell‐derived neurotrophic factor (GDNF); ciliary neurotrophic factor (CNTF); brain‐derived neurotrophic factor (BDNF); nerve growth factor (NGF); neurotrophin‐3 (NT‐3); neurotrophin‐4 (NT‐4); brain‐derived ...
Han Wu   +3 more
wiley   +1 more source

RGS14 (414)-mediated prevention of an episodic memory loss: a study of molecular mechanism [PDF]

open access: yes, 2015
A large proportion of human populations suffer memory impairments either caused by normal aging or afflicted by diverse neurological and neurodegenerative diseases. Memory enhancers and other drugs tested so far against memory loss have failed to produce
Navarro Lobato, Irene
core   +1 more source

Transphosphorylation of the Neurotrophin Trk Receptors [PDF]

open access: hybrid, 1996
Marco Canossa   +2 more
openalex   +1 more source

Role of Serum Brain‐Derived Neurotrophic Factor as a Biomarker of Chronic Pain in Older Adults

open access: yesEuropean Journal of Pain, Volume 29, Issue 5, May 2025.
ABSTRACT Background Serum brain‐derived neurotrophic factor (BDNF) has emerged as a promising biomarker for chronic pain (CP) research and treatment. Yet, most human studies have been limited by small sample sizes, inadequate control of confounders and a lack of focus on sex and mental health differences.
R. Ortolá   +9 more
wiley   +1 more source

Sleep Disturbance and Chronic Urticaria: A Narrative Review of Its Relationship, Treatment and Evolving Literature

open access: yesHealth Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims Chronic Spontaneous Urticaria is characterized by the sudden onset of itchy wheals and angioedema and is primarily driven by mast cells. It can have a significant impact on the Quality of Life (QoL) of an individual. While the role of mast cells in urticaria is extensively described, the link between sleep disorders and ...
Asad Ullah Wasim   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy