Results 261 to 270 of about 44,486 (289)
Some of the next articles are maybe not open access.
Current Opinion in Pulmonary Medicine, 2001
The neurotrophins are a family of peptides that promote survival, growth, and differentiation of neurons. Neurotrophins may also influence the function of nonneuronal cell types, including immune cells. The development and maintenance of asthma is thought to involve the nervous system and the immune system, but the role that neurotrophins play in ...
Bradley J. Undem +2 more
openaire +3 more sources
The neurotrophins are a family of peptides that promote survival, growth, and differentiation of neurons. Neurotrophins may also influence the function of nonneuronal cell types, including immune cells. The development and maintenance of asthma is thought to involve the nervous system and the immune system, but the role that neurotrophins play in ...
Bradley J. Undem +2 more
openaire +3 more sources
Neurotrophins and Neurotrophin Receptors in Human Pulmonary Arteries
Journal of Vascular Research, 2000The localization of neurotrophins (NTs) and NT receptors was analyzed in sections of human extra- and intrapulmonary arteries by Western blot analysis and immunohistochemistry. In extrapulmonary branches of human pulmonary artery, NT and NT receptor immunoreactivity was located in the tunica intima, within endothelium, in the tunica media, within ...
RICCI, Alberto +7 more
openaire +5 more sources
2003
Nerve growth factor was the first identified protein with anti-apoptotic activity on neurons. This prototypic neurotrophic factor, together with the three structurally and functionally related growth factors brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT3) and neurotrophin-4/5 (NT4/5), forms the neurotrophin protein family. Target T cells
Georg, Dechant, Harald, Neumann
openaire +2 more sources
Nerve growth factor was the first identified protein with anti-apoptotic activity on neurons. This prototypic neurotrophic factor, together with the three structurally and functionally related growth factors brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT3) and neurotrophin-4/5 (NT4/5), forms the neurotrophin protein family. Target T cells
Georg, Dechant, Harald, Neumann
openaire +2 more sources
Neurotrophins and schizophrenia
Schizophrenia Research, 2007Neurotrophins have established roles in neuronal development, synaptogenesis, and response to stress/anxious stimuli. Moreover, these agents are neuromodulators of monoaminergic, GABAergic, and cholinergic systems. Amidst a growing appreciation of the developmental neurobiology of schizophrenia--as well as the propensity for progressive brain changes ...
Sahebarao P. Mahadik +3 more
openaire +3 more sources
Physiology of the Neurotrophins
Annual Review of Neuroscience, 1996The neurotrophins are a small group of dimeric proteins that profoundly affect the development of the nervous system of vertebrates. Recent studies have established clear correlations between the survival requirements for different neurotrophins of functionally distinct subsets of sensory neurons.
Lewin, G. R., Barde, Y. A.
openaire +3 more sources
The neurotrophins and their receptors
Trends in Cell Biology, 1993The neurotrophins, which include nerve growth factor (NGF) and its relatives, were discovered and characterized for their distinctive ability to promote survival and differentiation of postmitotic neurons. Perhaps surprisingly, the neurotrophins have recently been found to utilize a family of receptor tyrosine kinases (the Trks) similar to those used ...
David J. Glass, George D. Yancopoulos
openaire +3 more sources
Neurotrophins and Neurotrophin Receptors in Human Lung Cancer
American Journal of Respiratory Cell and Molecular Biology, 2001The expression of neurotrophins (NTs) and related high- and low-affinity receptors was studied in surgical samples of histologically diagnosed human tumors of the lower respiratory tract. The experiment was conducted with 30 non-small cell lung cancer specimens and in eight small cell lung cancer specimens by Western blot analysis and ...
RICCI, Alberto +9 more
openaire +5 more sources
Neurotrophins and neurotrophin receptors in allergic asthma
2004The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 (NT-3) and NT-4 play a pivotal role in the development of the nervous system. Despite their well-known effects on neurons, elevated neurotrophin concentrations have been observed under pathological conditions in sera of patients with inflammatory disorders ...
Armin Braun +2 more
openaire +2 more sources
Functional Interactions of Neurotrophins and Neurotrophin Receptors
Annual Review of Neuroscience, 1995Hypothesis Programmed neuronal cell death is a prominent feature of vertebrate embryonic development. Timing and extent of cell death are dependent on the influence of the targets those neurons innervate, The number of neurons in the adult nervous system and the density of innervation of their targets are determined by a competitive process in which ...
openaire +3 more sources
Neurotrophin and Neurotrophin Receptors in Islet Cells
Hormone and Metabolic Research, 1997A large number of proteins are found specifically in insulin-producing cells and in neuronal cells. The function of neurotrophins in beta cells and the molecular mechanism leading to their expression include the expression of functional receptors for different neurotrophins.
openaire +3 more sources