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The Neurovascular Unit

2017
Abstract The neurovascular unit is a conceptual framework that emphasizes the importance of cell–cell signaling between neuronal, glial, and vascular cells for CNS function and dysfunction. During development, interactions between these multiple cell types provide the signals and substrates for CNS growth and maturation.
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Proteomes and Biomarkers of the Neurovascular Unit

2017
Brain vessels display a distinct phenotype that includes tight junctions and barrier properties of brain endothelial cells, as well as their close association with glial cells and neurons that enable tight coupling of blood flow with brain tissue energy demand.
Haqqani, A. S., Stanimirovic, D. B.
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A bidirectional model for communication in the neurovascular unit

Journal of Theoretical Biology, 2012
The neurovascular unit is a coordinated and interactional system of neurons, astrocytes, and microvessels in the brain. A central autoregulation mechanism observed in this unit is functional hyperemia, in which the microvasculature dilates in response to local neural activity in order to meet the increased demand for blood flow and oxygen.
Witthoft, Alexandra   +1 more
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Introduction to the neurovascular unit

Journal of Cerebral Blood Flow & Metabolism, 2005
For many years, a neurocentric view toward mechanisms of ischemic brain injury and repair has significantly contributed to our knowledge of the molecular pathways of excitotoxicity, oxidative stress and apoptosis. However, translation of these laboratory results into clinically effective stroke treatments remains a major challenge.
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Cell–cell Signaling in the Neurovascular Unit

Neurochemical Research, 2007
Historically, the neuron has been the conceptual focus for almost all of neuroscience research. In recent years, however, the concept of the neurovascular unit has emerged as a new paradigm for investigating both physiology and pathology in the CNS. This concept proposes that a purely neurocentric focus is not sufficient, and emphasizes that all cell ...
Josephine, Lok   +6 more
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The “Neuro-Glial-Vascular” Unit: The Role of Glia in Neurovascular Unit Formation and Dysfunction

Frontiers in Cell and Developmental Biology, 2021
John Greenwood   +2 more
exaly  

Neurovascular Unit

2010
Anne M Andrews   +136 more
openaire   +1 more source

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