Results 31 to 40 of about 3,790,471 (295)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Data‐Driven Satellite Drag Modeling Without Dynamic Knowledge of the Atmosphere

Space Weather
Increasing congestion in low Earth orbit (LEO) from new satellite deployments and a growing debris population has made accurate orbital trajectory prediction essential for anticipating and avoiding potential collisions on a regular basis.
William E. Parker, Richard Linares
doaj   +1 more source

Mesosphere and Lower Thermosphere (MLT) Density Responses to the May 2024 Superstorm at Mid-to-High Latitudes in the Northern Hemisphere Based on Sounding of the Atmosphere Using Broadband Emission Radiometry (SABER) Observations

Remote Sensing
The thermospheric density response during geomagnetic storms has been extensively explored, but with limited studies on the density response in the Mesosphere and Lower Thermosphere (MLT) region.
Ningtao Huang, Jingyuan Li, Jianyong Lu, Shuai Fu, Meng Sun, Guanchun Wei, Mingming Zhan, Ming Wang, Shiping Xiong   +8 more
doaj   +1 more source

Reactivity in ion-neutral high density media

EPJ Web of Conferences, 2016
The recent development of hybrid traps technology has revolutionized the field of cold chemistry. Recently, new trap configurations have been built in order to explore more involve chemical processes, among them is the three-body recombination involving ...
Pérez-Ríos J., Greene C. H.
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Studies of the low-energy neutral behavior using the low-energy neutral particle analyzer on EAST

Nuclear Materials and Energy, 2022
The neutral energy spectrums with an energy range of 20–3000 eV was measured by the low energy neutral particle analyzer (LENPA) in the 2021 EAST summer campaign.
N.X. Liu, R. Ding, L. Mu, R. Yan, J. Peng, B.F. Gao, Y. Zhang, K.X. Ye, T. Zhang, Y.F. Jin, J.L. Chen   +10 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Thermospheric Conditions Associated With the Loss of 40 Starlink Satellites

Space Weather, 2022
We analyzed far ultraviolet data from Defense Meteorological Satellite Program (DMSP)/Special Sensor Ultraviolet Spectrographic Imager (SSUSI) and Thermosphere Ionosphere Mesosphere Energetics and Dynamics (TIMED)/Global Ultraviolet Imager (GUVI) and ...
Yongliang Zhang, Larry J. Paxton, Robert Schaefer, William H. Swartz   +3 more
doaj   +1 more source