Results 51 to 60 of about 779,578 (304)

Temperature enhancements and vertical winds in the lower thermosphere associated with auroral heating during the DELTA campaign [PDF]

, 2009
A coordinated observation of the atmospheric response to auroral energy input in the polar lower thermosphere was conducted during the Dynamics and Energetics of the Lower Thermosphere in Aurora (DELTA) campaign.
Kurihara, J., Abe, T., Y. Ogawa, Oyama, K.-I., S. Oyama, S. Nozawa, T. T. Tsuda, T. Abe, Nozawa, S., Griffin, E., N. Iwagami, H. Miyaoka, E. Griffin, R. Fujii, Tsuda, T. T., K.-I. Oyama, Kauristie, K., Kosch, Mike J., Aruliah, A., Iwagami, N., J. Kurihara, A. Aruliah, Oyama, S., Miyaoka, H., Ogawa, Y., Fujii, R., M. J. Kosch, K. Kauristie   +27 more
core   +1 more source

X‐Raying Neutral Density Disturbances in the Mesosphere and Lower Thermosphere Induced by the 2022 Hunga‐Tonga Volcano Eruption‐Explosion

Geophysical Research Letters
We present X‐ray observations of the upper atmospheric density disturbance caused by the explosive eruption of the Hunga Tonga‐Hunga Ha'apai (HTHH) volcano on 15 January 2022.
Satoru Katsuda, Hiroyuki Shinagawa, Hitoshi Fujiwara, Hidekatsu Jin, Yasunobu Miyoshi, Yoshizumi Miyoshi, Yuko Motizuki, Motoki Nakajima, Kazuhiro Nakazawa, Kumiko K. Nobukawa, Yuichi Otsuka, Atsushi Shinbori, Takuya Sori, Chihiro Tao, Makoto S. Tashiro, Yuuki Wada, Takaya Yamawaki   +16 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Estimates of Spherical Satellite Drag Coefficients in the Upper Thermosphere During Different Geomagnetic Conditions

Space Weather
Satellite drag coefficients are crucial for determining the neutral mass densities that affect spacecraft operations in the thermosphere. Many studies typically utilize a constant drag coefficient of 2.2 to calculate the neutral density.
Xin Wang, Tingling Ren, Ronglan Wang, Bingxian Luo, Ercha Aa, Lei Cai, Ming Li, Juan Miao, Siqing Liu, Jiancun Gong   +9 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Algorithmic Improvements to Finding Approximately Neutral Surfaces

Journal of Advances in Modeling Earth Systems, 2021
Interior oceanic motions occur predominantly along, rather than across, the neutral tangent plane. These planes do not link together to form well‐defined surfaces, so oceanographers use approximately neutral surfaces.
Geoffrey J. Stanley, Trevor J. McDougall, Paul M. Barker   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Thermospheric Density, Composition, and Temperature From GOES‐R/SUVI Solar Occultations

Space Weather
A new data set of atomic oxygen (O) and molecular nitrogen (N2) number density profiles, along with thermospheric temperature profiles between 180 and 500 km, has been developed.
R. H. A. Sewell, E. M. B. Thiemann, J. Lafyatis, K. Hallock, C. Bethge, M. Pilinski, E. K. Sutton, C. L. Peck, D. B. Seaton   +8 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Satellite Reentry Predictions During Sudden Stratospheric Warmings

Space Weather
Prediction of uncontrolled satellite reentry time and trajectory are essential to avoid damages to human being and properties over land. Reentry time and trajectory are largely controlled by aerodynamic drag and mass neutral density below 200 km. In this
Jia Yue, Sean Bruinsma, Jack Wang, Nicholas Pedatella, Wandi Yu, Jean‐Charles Marty, Maria Kuznetsova   +6 more
doaj   +1 more source