Results 51 to 60 of about 38,595 (171)
CPT: Pharmacometrics & Systems Pharmacology, 2020 Incretin hormones glucagon‐like peptide‐1 (GLP‐1) and glucose‐dependent insulinotropic polypeptide (GIP) play a major role in regulation of postprandial glucose and the development of type 2 diabetes mellitus.
Pavel Balazki +3 more
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Journal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.ABSTRACT Ulcerative colitis (UC) is a chronic, inflammatory bowel disease with limited clinical treatment. Traditional Chinese medicinal ingredients honokiol and magnolol have potential anti‐inflammatory and gastrointestinal protective effects. However, their anti‐inflammatory potential has not been investigated in UC.
Zhaoxu Cai +5 more
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Transcriptomic prey‐capture responses in convergently evolved carnivorous pitcher plants
New Phytologist, Volume 249, Issue 5, Page 2559-2573, March 2026.Summary The Australian pitcher plant Cephalotus and the Asian pitcher plant Nepenthes exhibit striking morphological and functional similarities, serving as compelling examples of convergent evolution. Although trapping pitchers in both lineages represent some of the most elaborate leaf structures in angiosperms, it remains unknown whether their ...
Takanori Wakatake, Kenji Fukushima
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Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives
PROTEOMICS, Volume 26, Issue 2-3, Page 33-80, February 2026.ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto +2 more
wiley +1 more source
Spotlight on valsartan–sacubitril fixed-dose combination for heart failure: the evidence to date
Drug Design, Development and Therapy, 2016 José Fernando Vilela-Martin Internal Medicine Department, São José do Rio Preto State Medical School (FAMERP), São José do Rio Preto, Brazil Abstract: Heart failure is a global problem with elevated prevalence, and it
Vilela-Martin JF
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Frontiers in Microbiology, 2020 NprR is a protein of Bacillus anthracis that exhibits moonlighting functions as either a phosphatase or a neutral protease regulator that belongs to the RNPP family.
Yanchun Wang +6 more
doaj +1 more source
Chemical Biology &Drug Design, Volume 107, Issue 2, February 2026.Pharmacophore‐based virtual screening and molecular dynamics identified pentagalloylglucose and tannic acid as potent, non‐toxic neprilysin inhibitors. These natural compounds demonstrated strong binding affinity and stable interactions with the catalytic Zn2+ site, offering promising leads for cardiovascular drug development. ABSTRACT Neprilysin (NEP),
Chung‐Ting Kuo +4 more
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Indian Pacing and Electrophysiology Journal, 2008 Introduction We examined the acute effects of neutral endopeptidase inhibitor on the hemodynamics and electrical properties of dogs subjected to rapid atrial pacing.
Ryuta Imaki +6 more
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ATF4-mediated histone deacetylase HDAC1 promotes the progression of acute pancreatitis
Cell Death and Disease, 2021 Acute pancreatitis (AP), an acute inflammatory process, can be difficult to diagnose. Activating transcription factor 4 (ATF4) has been reported to participate in the pathogenesis of AP.
Xiaofeng Deng +3 more
doaj +1 more source
Advanced Healthcare Materials, Volume 15, Issue 2, 14 January 2026.Thiolated hyaluronic acid (HAMS) synthesized and characterized by NMR, solubility, thiol content, and pKa, is degraded by Staphylococcal hyaluronate lyase but not by mammalian hyaluronidase. Coating polyphosphate–M23 phage endolysin nanoparticles (M23‐PP) with HAMS confers Staphylococcus aureus responsiveness.
Mariana Blanco Massani +11 more
wiley +1 more source