Results 161 to 170 of about 401,069 (276)

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu   +10 more
wiley   +1 more source

Functional and antigenic constraints on the Nipah virus fusion protein. [PDF]

open access: yesProc Natl Acad Sci U S A
Larsen BB   +5 more
europepmc   +1 more source

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He   +10 more
wiley   +1 more source

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

open access: yesAdvanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij   +8 more
wiley   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

open access: yesAdvanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li   +9 more
wiley   +1 more source

Decoding antibody response to MERS-CoV in wild dromedary camels. [PDF]

open access: yesProc Natl Acad Sci U S A
Idoudi F   +18 more
europepmc   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre   +3 more
wiley   +1 more source

Antigenicity of key hepatitis C virus E1E2 glycoprotein neutralizing sites is genotype independent. [PDF]

open access: yesJ Gen Virol
Mimms JL   +13 more
europepmc   +1 more source

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