Results 51 to 60 of about 95,434 (266)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Construction, operation and performance of a chamber for tests of accelerated carbonation

open access: yesRevista Técnica de la Facultad de Ingeniería, 2010
Carbonation phenomenon produces first neutralization of the cement paste and later reinforcement corrosion in concrete structures. Its reaction mechanism is controlled by diffusional steps, which yield a rate which requires several years to obtain an ...
Douglas Linares, Miguel Sánchez
doaj  

Preparation and Characterization of Lanthanum Carbonate Octahydrate for the Treatment of Hyperphosphatemia

open access: yesJournal of Spectroscopy, 2013
We proposed a new approach to prepare lanthanum carbonate via reactions between lanthanum chloride and NaHCO3. In the reaction, small amount of NaHCO3 solution was firstly added to the acidic lanthanum chloride solution to generate lanthanum carbonate ...
Anqi He   +13 more
doaj   +1 more source

New Perspectives in Therapy of Intoxications by Organophosphoric Compounds

open access: yesEurasian Chemico-Technological Journal, 2003
Little references actually exist on neutralization therapy which could constitute the missing ring from an efficient treatment. As structural model capable to interact with organophosphoric substances, at the level of phosphor (P) atom, the common ...
V. Sunel   +3 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Immunity in trypanosomiasis I. Neutralization reaction

open access: yesParasitology, 1957
A study of neutralization reaction of trypanosomes with immune sera made against them is recorded, together with a description of the technique.Neutralizing antibody appears in rabbits infected withT. brucei5 days after infection and reaches its peak (1/320) within 28 days.The same titre of neutralizing antibody can be produced in rabbits by a series ...
openaire   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Feeling more neutral? Evaluative conditioning can increase neutral affective reactions

open access: yesCognition and Emotion
While it is important to learn what is good and bad, can people learn what is neither? The answer to this question is not readily apparent, but it has important implications for how people learn affective responses. Six experiments examined whether evaluative conditioning (EC) can instill neutral affect.
Karen Gasper, Danfei Hu, Elise Haynes
openaire   +2 more sources

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