Results 291 to 300 of about 1,883,437 (383)

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Engineering a TGEV S-trimer chimera with PEDV D0-NTD generates potent neutralizing antibodies against both viruses. [PDF]

J Virol
Zhang D, Yuan Y, Hu G, Xie Y, Meng X, Zhang Z, Zhang Y, Liao Q, Gebremariam AA, Shen H, Peng G, Shi Y.   +11 more
europepmc   +1 more source

Identification of CD4-Binding Site Dependent Plasma Neutralizing Antibodies in an HIV-1 Infected Indian Individual

, 2015
Lubina Khan, Muzamil Ashraf Makhdoomi, Sanjeev Kumar, Ambili Nair, Raiees Andrabi, Brenda E. Clark, Kate Auyeung, Jayanta Bhattacharya, Madhu Vajpayee, Naveet Wig, Ralph Pantophlet, Kalpana Luthra   +11 more
openalex   +2 more sources

Structural Identification of the Electrostatic Hot Spots for Severe Acute Respiratory Syndrome Coronavirus Spike Protein to Be Complexed with Its Receptor ACE2 and Its Neutralizing Antibodies

, 2020
Wei Li
openalex   +1 more source

Resistance of Bacteriophage to Neutralizing Antibody

Nippon Saikingaku Zasshi, 1954
openaire   +3 more sources

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Modulate the Course of Peritoneal Inflammation Through Metabolic and Epigenetic Regulation

Advanced Science, EarlyView.
MSC‐EVs alleviate peritoneal inflammation and fibrogenesis by disrupting the H3K18la‐CCL2 axis and crosstalk between mesothelial cells and Ly6c2⁺ macrophages. Model cartoons are constructed using the Biorender website (https://www.biorender.com/), and a usage license is obtained. Abstract Peritoneal dialysis (PD), as a renal replacement therapy, relies
Qiang Huang, Yuxiang Sun, Pengpeng Kuang, Juan Sun, Dandan Guo, Long Peng, Hu Zhou, Qinrong Song, Zhihao Huo, Canming Li, Janusz Witowski, Zhaoyong Hu, Hui Peng   +12 more
wiley   +1 more source

Parallel HIV-1 fitness landscapes shape viral dynamics in humans and macaques that develop broadly neutralizing antibodies. [PDF]

Elife
Shimagaki KS, Lynch RM, Barton JP.
europepmc   +1 more source

Tumor‐Derived Interleukin 35 Promotes Fibrosis in the Tumor Microenvironment of Pancreatic Cancer by Activating Pancreatic Stellate Cells

Advanced Science, EarlyView.
This study demonstrates that tumor‐derived IL‐35 promotes pancreatic cancer fibrosis by indirectly activating pancreatic stellate cells through IGFBP2/IGF‐1R/PI3K‐Akt and Tsp‐1/TGF‐β pathways. IL‐35 blockade reduces stromal fibrosis, restores chemosensitivity, and synergizes with gemcitabine‐based regimens, highlighting IL‐35 as a promising therapeutic
Hui Li, Huizhi Sun, Jing Liu, Yan Wu, Lin Wei, Jianming Li, Yudong Yuan, Peng Xie, Chao Xu, Guolu Luo, Yuqi Guan, Yukuan Feng, Antao Chang, Jihui Hao, Chongbiao Huang   +14 more
wiley   +1 more source

A paradigm shift in simulating affinity maturation to elicit broadly neutralizing antibodies. [PDF]

Front Immunol
Nakarin F, Sprenger KG.
europepmc   +1 more source

Neutralizing Antibody Titers to Epizootic and Non-epizootic Strains of Ibaraki Virus in Cattle within the Epizootic Region

, 2000
Yukinori UCHINUNO, Kazuki Ishibashi, Yasuharu HIRAKI, Keiichi Goto, Eiji Takagi   +4 more
openalex   +2 more sources