Results 271 to 280 of about 309,985 (359)

Development of a Blocking ELISA for Detection of Serum Neutralizing Antibodies Against Duck Adenovirus Type 3. [PDF]

Microorganisms
Tang M, Shi X, Xiong Y, Yuan C, Zhu Q, Huang M, Xu B, Liu Q, Pan X, Zhang Z, Teng Q, Yan M, Yan D, Li Z.   +13 more
europepmc   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Leveraging a Meta-Learning Strategy to Advance the Accuracy of Neutralizing Antibodies against Dengue Virus Serotype Prediction. [PDF]

ACS Omega
Charoenkwan P, Pipattanaboon C, Schaduangrat N, Mahmud SMH, Shoombuatong W.   +4 more
europepmc   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Versatile HIV Rev-dependent reporter cell system for stringent and sensitive quantification of viral reservoirs, neutralizing antibodies, and restriction factors. [PDF]

Retrovirology
Spear M, Choi J, Hetrick B, Lee J, Lê-Bury G, Vo TT, Han Y, Liang H, Guo J, Yu D, Iyer S, Mwandumba HC, Russell DG, Wu Y, Gludish DW.   +14 more
europepmc   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Monoclonal neutralizing antibodies elicited by infection with Kaposi sarcoma-associated herpesvirus reveal critical sites of vulnerability on gH/gL. [PDF]

PLoS Pathog
Wan YH, Pernikoff S, Aldridge NT, Lang K, Dudley HM, Scharffenberger SC, Kher G, Phipps W, Pancera M, Boonyaratanakornkit J, McGuire AT.   +10 more
europepmc   +1 more source

Maturation of West Nile Virus Modulates Sensitivity to Antibody-Mediated Neutralization

, 2008
Steevenson Nelson, Christiane A. Jost, Qinq Xu, Jessica Ess, Julie E. Martin, Theodore Oliphant, Stephen S. Whitehead, Anna P. Durbin, Barney S. Graham, Michael Diamond, Theodore C. Pierson   +10 more
openalex   +2 more sources