Results 111 to 120 of about 195,460 (295)

A Pseudo‐Mytilus Edulis Foot Protein‐Based Hydrogel Adhesive with Osteo‐Vascular‐Immune Coupling Effects for Osteoporotic Bone‐Implant Integration

open access: yesAdvanced Materials, EarlyView.
Inspired by mussel proteins, YDC‐Gel‐Zn is a smart bone glue designed for osteoporotic implants. It adheres strongly to both metal implants and bone for initial fixation. In osteoporosis's inflammatory environment, it sequentially releases zinc ions and therapeutic peptides: the zinc modulates immune cells to reduce inflammation, while the peptides ...
Wentao Wang   +9 more
wiley   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Preparation and neutralization efficacy of IgY antibodies raised against Deinagkistrodon acutus venom [PDF]

open access: gold, 2017
Jinhua Liu   +9 more
openalex   +1 more source

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

open access: yesAdvanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon   +21 more
wiley   +1 more source

Preparation and application of porcine broadly neutralizing monoclonal antibodies in an immunoassay for efficiently detecting neutralizing antibodies against foot-and-mouth disease virus serotype O

open access: yesMicrobiology Spectrum
Neutralizing antibodies provide vital protection against foot-and-mouth disease virus (FMDV). The virus neutralization test (VNT) is a gold standard method for the detection of neutralizing antibodies.
Yimei Cao   +19 more
doaj   +1 more source

Neutralizing monoclonal antibodies for treatment of COVID-19 [PDF]

open access: bronze, 2021
Peter C. Taylor   +5 more
openalex   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

In vivo determination of protective antibody thresholds for SARS-CoV-2 variants using mouse models

open access: yesEmerging Microbes and Infections
Neutralizing antibody titres have been shown to correlate with immune protection against COVID-19 and can be used to estimate vaccine effectiveness. Numerous studies have explored the relationship between neutralizing antibodies and protection.
Peilan Wei   +26 more
doaj   +1 more source

Home - About - Disclaimer - Privacy