Results 151 to 160 of about 300,221 (330)

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Assessment of the ability of HPV vaccines to induce neutralizing antibodies based on pseudovirus-based neutralization assay

Frontiers in Public Health
IntroductionHuman papillomavirus (HPV) infection represents a significant public health concern due to its strong association with various cancers and other diseases.
Zhihua Wu, Xuejie Li, Beibei Zhang
doaj   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

A Novel Recombinant Peste des Petits Ruminants-Canine Adenovirus Vaccine Elicits Long-Lasting Neutralizing Antibody Response against PPR in Goats

, 2012
Junling Qin, Hainan Huang, Yang Ruan, Xiaoqiang Hou, Songtao Yang, Chengyu Wang, Geng Huang, Tiecheng Wang, Na Feng, Yuwei Gao, Xianzhu Xia   +10 more
openalex   +2 more sources

Amine‐Functionalized Chitosan/dECM Composite Promotes Cutaneous Regeneration and Hair Follicle Activation by Regulating Oxidative Stress and Inflammation

Advanced Healthcare Materials, EarlyView.
An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim, Seokheon Hong, Jae Hwi Lee, Jongmin Lee, Jae Jun Kang, Jiseon Bae, Jino Kim, Dong‐Hwee Kim, Jin Yoo, Mi Sun Cha, Su Hee Kim, Youngmee Jung   +11 more
wiley   +1 more source

Poorly neutralizing polyclonal antibodyin vitroagainst coxsackievirus A16 circulating strains can prevent a lethal challengein vivo [PDF]

, 2018
Xin Yao, Qunying Mao, Yajing Li, Chunsheng Hao, Lianlian Bian, Pan Chen, Fan Gao, Xing Wu, Weiwei Lu, Qiang Gao, Xiuling Li, Zhenglun Liang   +11 more
openalex   +1 more source

Dendritic Cell‐Mediated Cross‐Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS‐CoV‐2 [PDF]

, 2023
Rodrigo Lázaro‐Gorines, Patricia Pérez, Ignacio Heras‐Murillo, Irene Adán‐Barrientos, Guillermo Albericio, David Astorgano, Sara Flores, Joanna Luczkowiak, Nuria Labiod, Seandean L. Harwood, Alejandro Segura‐Tudela, Laura Rubio‐Pérez, Yudhi Nugraha, Xiaoran Shang, Yuxing Li, Carlos Alfonso, Kaylin A. Adipietro, Dinendra L. Abeyawardhane, Rocío Navarro, Marta Compte, Wenbo Yu, Alexander D. MacKerell, Laura Sanz, David J. Weber, Francisco J. Blanco, Mariano Estéban, Edwin Pozharski, Raquel Godoy‐Ruiz, Inés G. Muñoz, Rafaël Delgado, David Sancho, Juan García‐Arriaza, Luis Álvarez‐Vallina   +32 more
openalex   +1 more source

Neutralization of HIV-1 by antibody

Current Opinion in Immunology, 1996
The humoral immune response to HIV-1 has been extensively studied over the past few years and considerable advances have been made in understanding the dynamics and specificity of the neutralizing antibody component during and after seroconversion. Despite this, there is still no clear understanding of the role of neutralizing antibodies in controlling
openaire   +2 more sources

Dendrimers Improve Apolipoprotein Nanoparticle mRNA Delivery to Immune Cells

Advanced Materials, EarlyView.
Apolipoprotein nanoparticle (aNP) platform technology efficiently delivers RNA to immune cells following systemic administration. Here, it is demonstrated that incorporating polyvalent ionizable cationic dendrimers in aNPs enables robust mRNA complexation and functional delivery.
Mirre M. Trines, Daniek Hoorn, Stijn R.J. Hofstraat, Robby C. Zwolsman, Tom Anbergen, Iris Versteeg, Yuri van Elsas, Jeroen Deckers, Merel M.A. Hendrikx, Teun Kleuskens, Youssef B. Darwish, Gijs W.B. Ros, Sjoerd F. Dijkstra, Bram Priem, Matt Timmers, P. Michel Fransen, Maarten J. Pouderoijen, Bas F.M. de Waal, E.W. Meijer, Thijs J. Beldman, Yohana C. Toner, Ewelina Kluza, Willem J.M. Mulder, Henk M. Janssen, Roy van der Meel   +24 more
wiley   +1 more source

Further Studies on the Effect of Neutralizing Antibody upon the Course of Herpes Simplex Infections in Tissue Culture [PDF]

, 1960
Clayton E. Wheeler, Charles M. Canby
openalex   +1 more source