Results 1 to 10 of about 2,582 (148)

Enhanced Resolution of Neutron Autoradiography with UV-C Sensitization to Study Boron Microdistribution in Animal Models [PDF]

Life, 2023
The assessment of boron microdistribution is essential to evaluate the suitability of boron neutron capture therapy (BNCT) in different biological models. In our laboratory, we have reported a methodology to produce cell imprints on polycarbonate through
Agustina Mariana Portu, María Sol Espain, Silvia Inés Thorp, Verónica Andrea Trivillin, Paula Curotto, Andrea Monti Hughes, Emiliano César Cayetano Pozzi, Marcela Alejandra Garabalino, Mónica Alejandra Palmieri, Pablo Nicolás Granell, Federico Golmar, Amanda Elena Schwint, Gisela Saint Martin   +12 more
doaj   +2 more sources

From nuclear track characterization to machine learning based image classification in neutron autoradiography for boron neutron capture therapy. [PDF]

PLoS ONE, 2023
Knowledge of the 10B microdistribution is of great relevance in BNCT studies. Since 10B concentration assesment through neutron autoradiography depends on the correct quantification of tracks in a nuclear track detector, image acquisition and processing ...
Julia S Viglietti, María S Espain, Rodrigo F Díaz, Luis A Nieto, Manuel Szewc, Guillermo C Bernardi, Luis M Rodríguez, Daniel E Fregenal, Gisela Saint Martin, Agustina M Portu   +9 more
doaj   +2 more sources

Synthesis and Characterization of Gd-Functionalized B₄C Nanoparticles for BNCT Applications [PDF]

Life, 2023
Inorganic nanoparticles of boron-rich compounds represent an attractive alternative to boron-containing molecules, such as boronophenylalanine or boranes, for BNCT applications. This work describes the synthesis and biological activity of multifunctional
Agostina Vitali, Maria Paola Demichelis, Greta Di Martino, Ian Postuma, Silva Bortolussi, Andrea Falqui, Chiara Milanese, Chiara Ferrara, Patrizia Sommi, Umberto Anselmi-Tamburini   +9 more
doaj   +2 more sources

Therapeutic Efficacy and Radiobiological Effects of Boric-Acid-Mediated BNCT in an Osteosarcoma-Bearing SD Rat Model [PDF]

Life, 2023
Background: Osteosarcoma (OS) is the most common primary malignancy of the bone and is notoriously resistant to radiation therapy. High-dose cytotoxic chemotherapy and surgical resection have improved the survival rate and prognosis of patients with OS ...
Chen-Fang Hsu, Hong-Ming Liu, Jinn-Jer Peir, Jiunn-Wang Liao, Kuan-Sheng Chen, Yi-Wei Chen, Yung-Jen Chuang, Fong-In Chou   +7 more
doaj   +2 more sources

A Novel Closo-Ortho-Carborane-Based Glucosamine Derivative as a Promising Agent for Boron Neutron Capture Therapy [PDF]

Pharmaceuticals
Background: Boron Neutron Capture Therapy (BNCT) is a promising cancer treatment that combines tumor-selective boron delivery agents with thermal neutrons to kill cancer cells while sparing normal tissue.
Daniela Imperio, Ian Postuma, Salvatore Villani, Erika Del Grosso, Laura Cansolino, Cinzia Ferrari, Silvia Fallarini, Silva Bortolussi, Luigi Panza   +8 more
doaj   +2 more sources

An improved neutron autoradiography set-up for (10)B concentration measurements in biological samples. [PDF]

Rep Pract Oncol Radiother, 2016
Boron Neutron Capture Therapy (BNCT) is a binary hadrontherapy which exploits the neutron capture reaction in boron, together with a selective uptake of boronated substances by the neoplastic tissue. There is increasing evidence that future improvements in clinical BNCT will be triggered by the discovery of new boronated compounds, with higher ...
Postuma I, Bortolussi S, Protti N, Ballarini F, Bruschi P, Ciani L, Ristori S, Panza L, Ferrari C, Cansolino L, Altieri S.   +10 more
europepmc   +6 more sources

Monte Carlo simulation-aided design of a thermal neutron generator system from 241Am-Be isotopic sources

Brazilian Journal of Radiation Sciences, 2023
Collimated thermal neutron beams are obtained from neutron extraction channels in nuclear reactors for various applications in research and technology, such as neutron imaging techniques (neutron radiography, neutron radioscopy, neutron tomography, and ...
Antônio Cezar Orozco, Claudio Antonio Federico, Odair Lelis Gonçalez   +2 more
doaj   +1 more source

Detection of phospholipids on paper chromatograms by neutron activation

Journal of Lipid Research, 1965
Improvements in the detection of phospholipids on paper chromatograms by neutron activation (with the formation of P32-compounds) have been made. Formaldehyde-treated papers were subjected to low neutron dosage after chromatographic development and the ...
Peter Johnson, Evelyn J. Weber, H.E. Carter, M.S. Krober   +3 more
doaj   +1 more source

Senescence in vitro and ionising radiations—the human diploid fibroblast model [PDF]

, 1981
The influence of ionising radiations on ageing is still controversial. Since Hayflick established the concept that diploid cells have finite lifespan in vitro, human diploid fibroblast (HDF) cultures have been recognised as a potent experimental model ...
A.F.G. Stevenson, Ban, Beer, Carrel, Cox, Cremer, Cristofalo, Ebeling, Finch, Fukushima, Guichard, Hayflick, Hayflick, Hayflick, Hoehn, Holliday, Holliday, Hopwood, Hug, Kaji, Kirkwood, Kirkwood, Laublin, Lima, Macieira-Coelho, Macieira-Coelho, Macieira-Coelho, Macieira-Coelho, Macieira-Coelho, Maisin, Martin, Namba, Nicholas, Orgel, Orgel, Russ, Schneider, Schneider, Smith, Stevenson, T. Cremer, Walburg, Weismann, Williams, Wilson   +44 more
core   +1 more source

Palladium, platinum, and gold distribution in serpentinite seamounts in the Mariana and Izu-Bonin forearcs: evidence from Leg 125 fluids and serpentinites

, 1992
Palladium, platinum, and gold were analyzed for 20 interstitial water samples from Leg 125. No Pd or Pt was detected in fluids from serpentinite muds from Conical Seamount in the Mariana forearc, indicating that low-temperature seawater-peridotite ...
Parkinson, I. J., Hall, G. E. M., Pearce, J. A.   +2 more
core   +2 more sources