Enhanced Resolution of Neutron Autoradiography with UV-C Sensitization to Study Boron Microdistribution in Animal Models [PDF]
Life, 2023 The assessment of boron microdistribution is essential to evaluate the suitability of boron neutron capture therapy (BNCT) in different biological models. In our laboratory, we have reported a methodology to produce cell imprints on polycarbonate through
Amanda Elena Schwint +2 more
exaly +4 more sources
From nuclear track characterization to machine learning based image classification in neutron autoradiography for boron neutron capture therapy. [PDF]
PLoS ONE, 2023 Knowledge of the 10B microdistribution is of great relevance in BNCT studies. Since 10B concentration assesment through neutron autoradiography depends on the correct quantification of tracks in a nuclear track detector, image acquisition and processing ...
Julia S Viglietti +9 more
doaj +2 more sources
Synthesis and Characterization of Gd-Functionalized B4C Nanoparticles for BNCT Applications [PDF]
Life, 2023 Inorganic nanoparticles of boron-rich compounds represent an attractive alternative to boron-containing molecules, such as boronophenylalanine or boranes, for BNCT applications. This work describes the synthesis and biological activity of multifunctional
Agostina Vitali +9 more
doaj +2 more sources
Therapeutic Efficacy and Radiobiological Effects of Boric-Acid-Mediated BNCT in an Osteosarcoma-Bearing SD Rat Model [PDF]
Life, 2023 Background: Osteosarcoma (OS) is the most common primary malignancy of the bone and is notoriously resistant to radiation therapy. High-dose cytotoxic chemotherapy and surgical resection have improved the survival rate and prognosis of patients with OS ...
Chen-Fang Hsu +7 more
doaj +2 more sources
A Novel Closo-Ortho-Carborane-Based Glucosamine Derivative as a Promising Agent for Boron Neutron Capture Therapy [PDF]
PharmaceuticalsBackground: Boron Neutron Capture Therapy (BNCT) is a promising cancer treatment that combines tumor-selective boron delivery agents with thermal neutrons to kill cancer cells while sparing normal tissue.
Daniela Imperio +8 more
doaj +2 more sources
Neutron capture autoradiography for a study on boron neutron capture therapy
Radiation Measurements, 2001 For the study on boron neutron capture therapy, CR-39 plastic track detectors attached with the whole-body sections of tumor bearing mice infused with 10B were exposed to thermal and cold neutron beams. Neutron capture autoradiographic images obtained by the cold neutron irradiation were extremely superior in quality than that of the thermal neutron ...
M Eriguchi, H Yanagië
exaly +4 more sources
Extending neutron autoradiography technique for boron concentration measurements in hard tissues [PDF]
Applied Radiation and Isotopes, 2018 The neutron autoradiography technique using polycarbonate nuclear track detectors (NTD) has been extended to quantify the boron concentration in hard tissues, an application of special interest in Boron Neutron Capture Therapy (BNCT). Chemical and mechanical processing methods to prepare thin tissue sections as required by this technique have been ...
Ian Postuma +2 more
exaly +5 more sources
Neutron autoradiography to study boron compound microdistribution in an oral cancer model
International Journal of Radiation Biology, 2015 We previously reported the therapeutic efficacy of Sequential Boron Neutron Capture Therapy (Seq-BNCT), i.e., BPA (boronophenylalanine) - BNCT followed by GB-10 (decahydrodecaborate) - BNCT 1 or 2 days later, in the hamster cheek pouch oral cancer model. We have utilized the neutron autoradiography methodology to study boron microdistribution in tissue.
Amanda Elena Schwint +2 more
exaly +4 more sources
An improved neutron autoradiography set-up for 10 B concentration measurements in biological samples [PDF]
Reports of Practical Oncology and Radiotherapy, 2016 Ian Postuma +2 more
exaly +2 more sources
Brazilian Journal of Radiation Sciences, 2023 Collimated thermal neutron beams are obtained from neutron extraction channels in nuclear reactors for various applications in research and technology, such as neutron imaging techniques (neutron radiography, neutron radioscopy, neutron tomography, and ...
Antônio Cezar Orozco +2 more
doaj +1 more source