Results 31 to 40 of about 220,141 (335)

G-CSF receptor (CSF3R) mutations in X-linked neutropenia evolving to acute myeloid leukemia or myelodysplasia

Haematologica, 2009
X-linked neutropenia (XLN) is a rare form of Congenital Neutropenia (CN) caused by inherited gain-of-function mutations of WAS. Here we report 2 cases of the original L270P X-linked neutropenia kindred that evolved to MDS or AML, with acquisition of G ...
Karolien Beel, Peter Vandenberghe
doaj   +1 more source

Febrile neutropenia in the emergency department

Current Medical Issues, 2021
Introduction: Febrile neutropenia is one of the most common presentations to the emergency department. Identification and empirical antibiotic therapy improve the outcome of these patients.
Malle Simeon, P Neeraj George Paul, Kundavaram Paul Prabhakar Abhilash   +2 more
doaj   +1 more source

Two Cases of Vancomycin-Induced Neutropenia

Pharmacy
(1) Background: The incidence of vancomycin-induced neutropenia in hospitalized patients is estimated to be around 2 to 8 percent Data surrounding vancomycin-induced neutropenia is limited as it is based on a small number of observational case reports ...
Kirsten Ganaja, Sarah Scoular, Staci Hemmer   +2 more
doaj   +1 more source

Efficacy and Safety of In-Asia-Manufactured rhG-CSF 300 mcg As Primary Prophylaxis for Prevention of CHOP Chemotherapy-induced Severe Neutropenia in Elderly Patients with Lymphoma Non-Hodgkin

Indonesian Journal of Cancer, 2009
We conducted open label, non-comparative trial in patients aged > 60 with advanced and intermediate-grade NonHodgkin Lymphoma (NHL) (stadium II, III, IV) to evaluate the efficacy and safety of In-Asia-manufactured rhG-CSF 300 mcg for prevention of CHOP (
Harryanto Reksodiputro, Zubairi Djoerban, Karmel L. Tambunan, Aru W. Sudoyo, Abidin Widjanarko, Djumhana Atmakusuma, Syafrizal Syafei, Nugroho Prayogo, Ronald Hukom, Dody Ranuhardy, Zakifman Jack, Asrul Harsal, Noorwati S, Bambang Karsono, Shufrie Effendi, Hilman Tadjoedin   +15 more
doaj   +1 more source

High efficacy and low toxicity of weekly docetaxel given as first-line treatment for metastatic breast cancer [PDF]

, 2005
Background: Docetaxel is one of the most effective antitumor agents currently available for the treatment of metastatic breast cancer (MBC). This phase II multicenter study prospectively analyzed the efficacy and toxicity of docetaxel given on a weekly ...
Ajani JA, Ando M, B. Dorn, C. Jackisch, C. Kentenich, Chan S, Chevallier B, Dieras V, G. Deutsch, Hainsworth JD, Hudis CA, J. Papke, J. Stamp, J. Stemmler, Kaplan EL, M. Malekmohammadi, M. Stauch, Nabholtz JM, O. Brudler, S. Leinung, Salminen E, Trudeau ME, U. Vehling-Kaiser, V. Heinemann, Valero V, W. Abenhardt, W. Mair   +26 more
core   +1 more source

KEJADIAN DEMAM NEUTROPENIA PADA PASIEN KANKER PAYUDARA YANG MENDAPAT KEMOTERAPI

Majalah Kedokteran Andalas, 2015
AbstrakKemoterapi memiliki peranan penting dalam penatalaksanaan kanker payudara. Obat ini bekerjamembunuh sel-sel kanker, namun dapat juga menghancurkan sel-sel sehat termasuk sel darahsehingga dapat menyebabkan neutropenia.
Rulli Firmansyah, Daan Khambri, Edison Edison, Zelly Dia Rofinda   +3 more
doaj   +1 more source

Aplastic Crisis as Primary Manifestation of Systemic Lupus Erythematosus [PDF]

, 2011
Aplastic crisis is an unusual feature of systemic lupus erythematosus (SLE). We report the case of a 54-year-old woman presenting with both (extravascular) Coombs-positive hemolytic anemia and laboratory findings of bone marrow hyporegeneration with ...
Alger M, Andreas Völkl, Bailey FA, Brooks, Chute JP, Espinoza JL, Feng X, Fuat S. Oduncu, Hinterberger-Fischer M, Hirano N, Hirano N, Mestanza-Peralta M, Michael Bäuerle, Pavithran K, Philipp Baumann, Ralf Schmidmaier, Singh NP, Tagoe C, Takamatsu H, Tan EM, Torok-Storb B, Wolach B, Young NS, Young NS   +23 more
core   +1 more source

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Simtuzumab in Combination with FOLFIRI for the Second-Line Treatment of Metastatic KRAS Mutant Colorectal Adenocarcinoma. [PDF]

, 2017
Lessons learnedThe safety profile in the patient groups who received FOLFIRI and simtuzumab did not differ from that in the FOLFIRI and placebo group.The addition of simtuzumab to chemotherapy with FOLFIRI does not improve clinical outcomes in patients ...
Bendell, Johanna, Benson, Al B, Hecht, J Randolph, Verma, Udit, Vyushkov, Dmitry, Yang, Yingsi   +5 more
core   +1 more source

Olanzapine-induced neutropenia [PDF]

Mental Illness, 2015
Olanzapine-induced neutropenia is a rare adverse effect that is currently poorly described in literature. Although neutropenia is a known adverse effect of clozapine, it has been associated with the use of other antipsychotic medications like olanzapine. This case report describes and reviews a case of olanza-pine-induced neutropenia in a schizophrenic
Kirti Malhotra, Priscilla Vu, Danielle H. Wang, Hank Lai, Lawrence R. Faziola   +4 more
openaire   +3 more sources