Results 81 to 90 of about 140,144 (311)

Características das infecções em indivíduos portadores de neoplasias hematológicas internados no Hospital Universitário Professor Polydoro Ernani de São Thiago [PDF]

open access: yes, 2014
Dissertação (mestrado profissional) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação Multidisciplinar em Saúde, Florianópolis, 2014.As neoplasias malignas do sistema hematopoiético atingem células ...
Almeida, Adriana Brejinski de
core  

Development of an application for the implementation, application and monitoring of the Instituto Nacional de Cancerología E.S.E.'s febrile neutropenia guideline.

open access: yes, 2023
La neutropenia febril es una complicación de la quimioterapia, sobre todo en pacientes con cáncer hematológico, con alto riesgo de morbimortalidad. Las guías de manejo hacen su abordaje más homogéneo.
Gómez Rincón, Julio César
core  

USB1 deficiency disrupts neutrophil maturation via RNA dysregulation independent of global pre‐mRNA splicing

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the essential role of USB1 in neutrophil maturation. In normal myeloid cells, USB1 acts as an RNA exonuclease, trimming RNA tails to maintain proper RNA network function, which supports the differentiation of myeloid progenitor cells into mature neutrophils.
Hang Li   +6 more
wiley   +1 more source

Level of Knowledge and Incidence of Emergency Oncology: Febrile Neutropenia in Hematologic Cancer Patients Post Chemotherapy: A Descriptive Study

open access: yesMasker Medika
Introduction: Febrile neutropenia is a life-threatening condition that is the most common oncological emergency, especially in cases of hematological cancer. Knowledge related to this condition can accelerate treatment and reduce mortality. The danger of
Agus Suryaman
doaj   +1 more source

What you need to know neutropenia and risk for infection [PDF]

open access: yes
Neutropenia, pronounced noo-troh-PEE-nee-uh, is a decrease in the number of white blood cells. These cells are the body\ue2\u20ac\u2122s main defense against infection.

core  

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

open access: yesArthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Isolated Severe Neutropenia in Adults, Evaluation of Underlying Causes and Outcomes, Real-World Data Collected over a 5-Year Period in a Tertiary Referral Hospital

open access: yesMedicina
Background and Objectives: In clinical practice, neutropenia is frequently accompanied by other cytopenia; isolated non-chemotherapy-induced severe neutropenia is less frequent and its differential diagnosis can be challenging.
Linet Njue   +5 more
doaj   +1 more source

Febrile Neutropenia

open access: yes, 2014
Pocketbook for Cancer Supportive Care Febrile Neutropenia is a comprehensive review on febrile neutropenia, its prevention, risks, management, costs, and special populations affected by the condition.
Klastersky, Jean
core   +1 more source

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk   +5 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis   +5 more
wiley   +1 more source

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