Results 171 to 180 of about 1,017,928 (387)

ECRG4 regulates neutrophil recruitment and CD44 expression during the inflammatory response to injury. [PDF]

open access: yes, 2020
The complex molecular microenvironment of the wound bed regulates the duration and degree of inflammation in the wound repair process, while its dysregulation leads to impaired healing. Understanding factors controlling this response provides therapeutic
Baird, Andrew   +5 more
core  

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

open access: yesAdvanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu   +7 more
wiley   +1 more source

A Twist in the Diagnosis: Chronic Arthropathy Without Inflammation

open access: yes
Arthritis Care &Research, EarlyView.
María Á. Puche‐Larrubia   +3 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

The Clinical Implication of Dynamic Hematological Parameters in COVID-19: A Retrospective Study in Chongqing, China

open access: yesInternational Journal of General Medicine, 2021
Huan Yang,1,2 Yuan Xu,2 Zhijie Li,2 Ling Yan,2 Jing Wang,3 Pu Liao1,2 1School of Clinical Medicine, Southwest Medical University, Luzhou, People’s Republic of China; 2Department of Clinical Laboratory, Chongqing General Hospital, Chonging, People’s ...
Yang H   +5 more
doaj  

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

open access: yesAdvanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz   +7 more
wiley   +1 more source

Neutrophil to High-Density Lipoprotein Ratio is Associated with Hemorrhagic Transformation in Patients with Acute Ischemic Stroke

open access: yesJournal of Inflammation Research, 2022
Ruirui Zhang,1 Fanfu Jin,1 Lanlan Zheng,1 Tingwei Liao,1 Guangling Guan,1 Jianfei Wang,1 Shoucai Zhao,1 Shizao Fei,2,* Zhaohu Chu,1,* Yang Xu1,3,* 1Department of Neurology, The First Affiliated Hospital of Wannan Medical College, Wuhu, People’
Zhang R   +9 more
doaj  

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

open access: yesAdvanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen   +30 more
wiley   +1 more source

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