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Neutrophil degranulation is increased at seven days after human intracerebral hemorrhage, but not at 72 h, and correlates with decreased miR-3613 and miR-3690. [PDF]
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Current Opinion in Immunology, 1989
In 'beneficial inflammation', which is the major component of our innate immune system, it is possible to predict an 'ideal' sequence of cellular events: neutrophil migration would be rapid; time of contact with endothelial cells minimized; matrix degradation localized, with specific turn-on and turn-off of degradation mechanisms; neutrophil secretion ...
C, Haslett, J S, Savill, L, Meagher
openaire +2 more sources
In 'beneficial inflammation', which is the major component of our innate immune system, it is possible to predict an 'ideal' sequence of cellular events: neutrophil migration would be rapid; time of contact with endothelial cells minimized; matrix degradation localized, with specific turn-on and turn-off of degradation mechanisms; neutrophil secretion ...
C, Haslett, J S, Savill, L, Meagher
openaire +2 more sources
Developmental & Comparative Immunology, 2021
Since inflammasomes were discovered in the early 21st century, knowledge about their biology has multiplied exponentially. These cytosolic multiprotein complexes alert the immune system about the presence of infection or tissue damage, and regulate the subsequent inflammatory responses.
Victoriano Mulero +2 more
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Since inflammasomes were discovered in the early 21st century, knowledge about their biology has multiplied exponentially. These cytosolic multiprotein complexes alert the immune system about the presence of infection or tissue damage, and regulate the subsequent inflammatory responses.
Victoriano Mulero +2 more
openaire +3 more sources
Neutrophil chemotactic activity of rabbit neutrophils
Archives of Oral Biology, 1974Abstract Neutrophils regularly migrate into crevices of both healthy and inflamed gingiva. In the presence of inflamed gingiva, dental plaque supplies substances with a chemotactic effect on neutrophils. but the substances responsible for the attraction of neutrophils to crevices of healthy gingiva have not been identified.
Gunilla Tynelius-Bratthall, J. Lindhe
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Neutrophil extracellular traps: neutrophil’s afterlife
Hirurg (Surgeon), 2021This paper is a literature review on the origin, structure and functioning of neutrophil extracellular traps (NETs) that are released from neutrophils through NETosis, the kind of cell death. NETs are comprised of DNA, histones and neutrophil granule enzymes.
Viacheslav Nikolaevich Kravchuk +7 more
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Microbes and Infection, 2003
Phagocytosis is central to the microbicidal function of neutrophils. Pathogens are initially engulfed into a plasma membrane-derived vacuole, the phagosome, which proceeds to acquire degradative properties by a complex process termed maturation. In this chapter, we discuss the current knowledge of the molecular mechanisms underlying phagosome formation
Rene E. Harrison +2 more
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Phagocytosis is central to the microbicidal function of neutrophils. Pathogens are initially engulfed into a plasma membrane-derived vacuole, the phagosome, which proceeds to acquire degradative properties by a complex process termed maturation. In this chapter, we discuss the current knowledge of the molecular mechanisms underlying phagosome formation
Rene E. Harrison +2 more
openaire +3 more sources
Gasdermin D plays a vital role in the generation of neutrophil extracellular traps
Science immunology, 2018By screening a library of compounds that block NETosis, we have identified a gasdermin D inhibitor. Casting NETs Gasdermin D (GSDMD), a pore-forming protein, has emerged as a key downstream effector in pyroptosis, a form of cell death induced by ...
G. Sollberger +12 more
semanticscholar +1 more source