Results 191 to 200 of about 152,807 (272)

Two randomised controlled phase 2 studies of the oral neutrophil elastase inhibitor alvelestat in alpha-1 antitrypsin deficiency. [PDF]

Eur Respir J
Wells JM, Titlestad IL, Tanash H, Turner AM, Chapman KR, Hatipoğlu UŞ, Goldklang MP, D'Armiento JM, Pirozzi CS, Drummond MB, Barjaktarevic IZ, Chatila WM, Devine MS, Strange C, Sandhaus RA, Parkin JM, Westfall E, Lin VY, Parks R, Kuo HC, Ekue A, Moffitt KL, Inshaw J, Aban I, Dransfield MT, Stockley RA.   +25 more
europepmc   +1 more source

Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Calcium phosphate biomineralization has traditionally been considered a protein‐regulated process. This review highlights the emerging role of nucleic acids, which interact with mineral phases through adsorption, coprecipitation, and templating, thereby influencing crystal nucleation and growth.
Fanny Duhalde, Jessem Landoulsi, Xavier Houard   +2 more
wiley   +1 more source

Neutrophil elastase promotes mucin secretion in airway epithelial cells through the MARCKS/ACK1/cortactin pathway. [PDF]

Cent Eur J Immunol
He M, Li Q, Ouyang S, Liu Y, Perelman JM, Kolosov VP, Zhou X, Li Y.   +7 more
europepmc   +1 more source

Neutrophil elastase promotes low molecular weight cyclin E1 formation to accelerate osteosarcoma proliferation. [PDF]

Front Immunol
Xu J, Shi Q, Zeng F, Ren T, Wei R, Tang X.   +5 more
europepmc   +1 more source

Neutrophil elastase activity in bronchial lavage fluid and the one-year follow-up outcomes in bronchiectasis patients: A multicenter prospective cohort study. [PDF]

Ther Adv Respir Dis
Nguyen-Ho L, Tran-Le QK, Trinh HKT, Vu DM, Le-Thuong V, Tran-Van N, Chalmers JD.   +6 more
europepmc   +1 more source

Neutrophils Induce P-Selectin Shedding from Activated Platelets Via Neutrophil Elastase. [PDF]

Inflammation
Huang Y, Ling L, He S, Liu C, Huang X, Wang S, Yu Z, Zhou J.   +7 more
europepmc   +1 more source

Identification of an exosite at the neutrophil elastase/alpha-1-antitrypsin interface. [PDF]

FEBS J
Gangemi R, Bignotti M, Denardo A, Pearce CN, Ronzoni R, Lomas DA, Irving JA, Fra A, Gangemi F.   +8 more
europepmc   +1 more source

Inhibition of proteinases with recombinant Eglin c during experimental Escherichia coli septicemia in the pig [PDF]

, 1989
Siebeck, Matthias, Jochum, Marianne, Fritz, Hans, Hoffmann, H.   +3 more
core   +1 more source

Role of neutrophil elastase in predicting infection among children with chemotherapy-induced febrile neutropenia. [PDF]

Clin Exp Pediatr
El-Hawy MA, Elian DM, El-Hamid MEA, Allam ET, Kandeel MS, Mahmoud AA.   +5 more
europepmc   +1 more source

A Rationally Designed Novel Bifunctional Human TNF-α- and Janus Kinase-Targeted soloMER Drug Conjugate (SDC) with a Neutrophil Elastase Cleavable Linker Delivering Inflammation Site-Specific Release of Payload. [PDF]

J Med Chem
Murray E, Priyanka S, Martinez-Fraile J, Grygorash R, Idress M, Brownbridge LC, Glavina S, Camper N, Boyd R, Porter AJ, Barelle CJ, Ubah OC.   +11 more
europepmc   +1 more source