Results 1 to 10 of about 18,108 (112)

Leukocyte elastase, a1-proteinase inhibitor, and autoantibodies to neuroantigens in diagnostics of endogenous depressive disorders [PDF]

European Psychiatry, 2022
Introduction It has been suggested that the activation of systemic inflammatory response in depression is associated with inflammatory changes in the brain (neuroinflammation) and may reflect the severity of the clinical symptoms in patients ...
Z. Sarmanova, N. Subbotskaya, S. Zozulya, A. Barkhatova, T. Klyushnik   +4 more
doaj   +2 more sources

Association of leukocyte elastase in semen and seminal plasma with sperm parameters and pregnancy outcomes in male fertility [PDF]

Endocrine Connections
Background: Semen analysis is the standard test for evaluating male fertility. However, it may not address all aspects of male infertility. This review explores the role of leukocyte elastase (LE) as a possible biomarker for male fertility by evaluating ...
Mausumi Das, Maha Gumssani, Julia Mullaney, Ralf Henkel, Suks Minhas, Marie Claire Aquilina, Channa N Jayasena   +6 more
doaj   +2 more sources

Eliminating circulating donor passenger leukocytes during clinical ex vivo lung perfusion does not attenuate inflammation [PDF]

JHLT Open
Purpose: During Ex Vivo Lung Perfusion (EVLP), it is standard practice to incorporate a leukocyte filter to remove donor passenger leukocytes and attenuate their inflammatory effects.
M.A. Hu, MD, Z.L. Zhang, MD, R.F. Hoffmann, PhD, C.T. Gan, MD PhD, E.A.M. Verschuuren, MD PhD, C. Van De Wauwer, MD PhD, H.G.D. Leuvenink, PhD, M.E. Erasmus, MD PhD   +7 more
doaj   +2 more sources

Exploration of Exercise-Induced Gastrointestinal Syndrome in Endurance-Trained Adolescents: Is There Cause for Concern in Regard to Ultra-endurance Event Participation [PDF]

Sports Medicine - Open
Background Exercise-induced gastrointestinal syndrome (EIGS) in response to prolonged exercise is well-established in adult athletes but no study has investigated how EIGS presents in adolescent athletes despite an increase in youth participation in ...
Pascale Young, Volker Scheer, Zoe Davidson, Jessica R. Biesiekierski, Ricardo J. S. Costa   +4 more
doaj   +2 more sources

A BODIPY-Tagged Phosphono Peptide as Activity-Based Probe for Human Leukocyte Elastase [PDF]

ACS Medicinal Chemistry Letters, 2018
Michael Gütschow, Annett Braune, Anna-Christina Schulz-Fincke   +2 more
exaly   +2 more sources

The hidden side of SERPINB1/Leukocyte Elastase Inhibitor

Seminars in Cell and Developmental Biology, 2017
Alicia Torriglia
exaly   +2 more sources

Genetic deficiency of protein inhibitor of activated STAT3 suppresses experimental abdominal aortic aneurysms

Frontiers in Cardiovascular Medicine, 2023
AimSignal transducer and activator of transcription (STAT) signaling is critical for the pathogenesis of abdominal aortic aneurysms (AAAs). Though protein inhibitor of activated STAT3 (PIAS3) negatively modulates STAT3 activity, but its role in AAA ...
Weilai Fu, Weilai Fu, Haole Liu, Panpan Wei, Panpan Wei, Congcong Xia, Congcong Xia, Qingqing Yu, Kangli Tian, Yankui Li, Enqi Liu, Baohui Xu, Masaaki Miyata, Rong Wang, Sihai Zhao, Sihai Zhao   +15 more
doaj   +1 more source

Proteolytic cleavage of HLA class II by human neutrophil elastase in pneumococcal pneumonia

Scientific Reports, 2021
Bacterial and viral respiratory infections can initiate acute lung injury and acute respiratory distress syndrome. Neutrophils and their granule enzymes, including neutrophil elastase, are key mediators of the pathophysiology of acute respiratory failure.
Hisanori Domon, Tomoki Maekawa, Toshihito Isono, Kazuyuki Furuta, Chikara Kaito, Yutaka Terao   +5 more
doaj   +1 more source

ESTIMATION OF LEVEL OF SUBPOPULATION CD14⁺/CD16⁺ MONOCYTES IN PATIENTS WITH JUVENILE DEPRESSIONS

Медицинская иммунология, 2019
At present, at least two phenotypically different subpopulations of blood monocytes have been identified: "classical" monocytes with the phenotype CD14++/CD16-  and "nonclassical" (pro-inflammatory) with the phenotype CD14+/CD16+. It has been established
E. F. Vasilyeva, T. P. Sekirina, Z. V. Sarmanova, S. A. Zozulya, M. A. Omel'chenko, T. P. Klushnik   +5 more
doaj   +1 more source

The role of plasma serine leukocyte proteinase inhibitor in the body's defense against COVID-19

Журнал микробиологии, эпидемиологии и иммунобиологии, 2021
The COVID-19 pandemic continues, causing colossal damage to the population and the global economy. As COVID-19 is studied, new data are emerging regarding the risk of severe coronavirus infection in patients with α1-antitrypsin deficiency.
A. L. Kravtsov, S. A. Bugorkova
doaj   +1 more source