Results 31 to 40 of about 123,303 (240)
Inhibition of neutrophil activity improves cardiac function after cardiopulmonary bypass [PDF]
, 2007 Background The arterial in line application of the leukocyte inhibition module (LIM) in the cardiopulmonary bypass (CPB) limits overshooting leukocyte activity during cardiac surgery.
Windolf Joachim +21 more
core +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Respiratory Research, 2000 Secretory leukocyte proteinase inhibitor and elafin are two low-molecular-mass elastase inhibitors that are mainly synthesized locally at mucosal sites. It is thought that their physicochemical properties allow them to efficiently inhibit target enzymes,
Sallenave Jean-Michel
doaj +1 more source
Forum of Clinical Oncology, 2020 Past decade has seen the advent of several prognosticators for oral squamous cell carcinoma (OSCC). Although TNM staging is still considered as the prognostic gold standard, it is not possible to obtain all the necessary information for a pathological ...
Jaiswal Pooja +6 more
doaj +1 more source
Paternal mosaicism proves the pathogenic nature of mutations in neutrophil elastase in severe congenital neutropenia [PDF]
, 2002 Heterozygous mutations in neutrophil elastase have been detected in many sporadic cases of congenital neutropenia. However, a convincing pathogenetic mechanism has not been established, and it is unclear whether the effects of the mutant enzyme occur ...
Ancliff, PJ +13 more
core +1 more source
New Polyketides from the Marine-derived Fungus
Natural Product Communications, 2009 The fungus Phaeosphaeria spartinae is an endophyte of the marine alga Ceramium sp. Investigation of this marine-derived fungus led to the isolation of the new natural products spartinol A (1), B (2), C (3) and D (4).
Mahmoud Fahmi Elsebai +3 more
doaj +1 more source
Long-Term Leukocyte Filtration Should Be Avoided during Extracorporeal Circulation
Mediators of Inflammation, 2013 Filtration during extracorporeal circulation (ECC) not only removes but also activates leukocytes; therefore, long-term leukocyte filtration may cause adverse effects.
Jiali Tang +6 more
doaj +1 more source
European Psychiatry, 2022 Introduction The clinical and biological studies indicate the involvement of inflammation in the pathogenesis of endogenous mental disorders. The inflammation markers leukocyte elastase, α1-proteinase inhibitor, and autoantibodies to neuroantigens ...
S. Zozulya +4 more
doaj +1 more source
Nonspecific protease and elastase activities in rat leukocytes [PDF]
Inflammation, 1982 Extracts were prepared from rat peritoneal leukocytes obtained 4 h after glycogen injection and assayed for proteolytic enzyme activities against various substrates. The substrates used included acid-denatured bovine hemoglobin, bovine serum albumin, a partially purified preparation of rat pulmonary basement membrane, bovine neck ligament elastin, and ...
Varani, James +2 more
openaire +3 more sources
Receptor‐mediated binding of leukocyte elastase by chondrocytes [PDF]
Arthritis & Rheumatism, 1987 AbstractStudies on the effect of leukocyte elastase on the metabolism of chondrocytes in culture have demonstrated that these cells possess a specific cell surface receptor for leukocyte‐derived elastase. Purified elastase from rabbit and human leukocytes is capable of modulating the metabolism of the cell by causing a marked decrease in both ...
J S, Bartholomew, D A, Lowther
openaire +2 more sources