Results 21 to 30 of about 17,148 (192)

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Type I Interferon Receptor Subunit 1 Deletion Attenuates Experimental Abdominal Aortic Aneurysm Formation

open access: yesBiomolecules, 2022
Objective: Type I interferon receptor signaling contributes to several autoimmune and vascular diseases such as lupus, atherosclerosis and stroke. The purpose of this study was to assess the influence of type I interferon receptor deficiency on the ...
Takahiro Shoji   +12 more
doaj   +1 more source

Single Intramammary Infusion of Recombinant Bovine Interleukin-8 at Dry-Off Induces the Prolonged Secretion of Leukocyte Elastase, Inflammatory Lactoferrin-Derived Peptides, and Interleukin-8 in Dairy Cows

open access: yesVeterinary Medicine International, 2012
A single intramammary infusion of recombinant bovine interleukin-8 (IL-8) at 50 μg/quarter/head, but not 10 μg/quarter/head, induced clinical mastitis in three of four cows during the dry-off period, resulting in an elevated rectal temperature, redness ...
Atsushi Watanabe   +4 more
doaj   +1 more source

Modulation of HIV Replication in Monocyte-Derived Macrophages (MDM) by Host Antiviral Factors Secretory Leukocyte Protease Inhibitor and Serpin Family C Member 1 Induced by Steroid Hormones

open access: yesViruses, 2022
The impact of steroid hormones estrogen and progesterone on human immunodeficiency virus type 1 (HIV-1) replication is well documented. However, the exact mechanism involved in the regulation of HIV-1 replication by estrogen and progesterone is still ...
Santanu Biswas   +5 more
doaj   +1 more source

The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skin-derived antileukoprotease) as alarm antiproteinases in inflammatory lung disease

open access: yesRespiratory Research, 2000
Secretory leukocyte proteinase inhibitor and elafin are two low-molecular-mass elastase inhibitors that are mainly synthesized locally at mucosal sites. It is thought that their physicochemical properties allow them to efficiently inhibit target enzymes,
Sallenave Jean-Michel
doaj   +1 more source

Assessing the potential role of neutrophil elastase as a prognostic indicator in oral squamous cell carcinoma

open access: yesForum of Clinical Oncology, 2020
Past decade has seen the advent of several prognosticators for oral squamous cell carcinoma (OSCC). Although TNM staging is still considered as the prognostic gold standard, it is not possible to obtain all the necessary information for a pathological ...
Jaiswal Pooja   +6 more
doaj   +1 more source

New Polyketides from the Marine-derived Fungus

open access: yesNatural Product Communications, 2009
The fungus Phaeosphaeria spartinae is an endophyte of the marine alga Ceramium sp. Investigation of this marine-derived fungus led to the isolation of the new natural products spartinol A (1), B (2), C (3) and D (4).
Mahmoud Fahmi Elsebai   +3 more
doaj   +1 more source

Long-Term Leukocyte Filtration Should Be Avoided during Extracorporeal Circulation

open access: yesMediators of Inflammation, 2013
Filtration during extracorporeal circulation (ECC) not only removes but also activates leukocytes; therefore, long-term leukocyte filtration may cause adverse effects.
Jiali Tang   +6 more
doaj   +1 more source

Association between markers of inflammation and indicators of systemic endotoxemia in endogenous psychosis

open access: yesEuropean Psychiatry, 2022
Introduction The clinical and biological studies indicate the involvement of inflammation in the pathogenesis of endogenous mental disorders. The inflammation markers leukocyte elastase, α1-proteinase inhibitor, and autoantibodies to neuroantigens ...
S. Zozulya   +4 more
doaj   +1 more source

The Role of Neutrophils and Neutrophil Extracellular Traps in Acute Pancreatitis

open access: yesFrontiers in Cell and Developmental Biology, 2021
Leukocyte invasion (neutrophils and monocytes/macrophages) is closely related to the severity of acute pancreatitis (AP) and plays an important role in the systemic inflammatory response and other organ injuries secondary to AP.
Jianhua Wan   +5 more
doaj   +1 more source

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