Results 11 to 20 of about 17,148 (192)

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research
This study investigated targeted antimicrobial delivery through enzyme‐responsive polyelectrolyte complex (PIC) nanoparticles of peptides and antimicrobials. Nanoparticles released chlorhexidine upon enzymatic activation by human leukocyte elastase (HLE),
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
doaj   +2 more sources

ESTIMATION OF LEVEL OF SUBPOPULATION CD14⁺/CD16⁺ MONOCYTES IN PATIENTS WITH JUVENILE DEPRESSIONS

Медицинская иммунология, 2019
At present, at least two phenotypically different subpopulations of blood monocytes have been identified: "classical" monocytes with the phenotype CD14++/CD16-  and "nonclassical" (pro-inflammatory) with the phenotype CD14+/CD16+. It has been established
E. F. Vasilyeva, T. P. Sekirina, Z. V. Sarmanova, S. A. Zozulya, M. A. Omel'chenko, T. P. Klushnik   +5 more
doaj   +1 more source

The role of plasma serine leukocyte proteinase inhibitor in the body's defense against COVID-19

Журнал микробиологии, эпидемиологии и иммунобиологии, 2021
The COVID-19 pandemic continues, causing colossal damage to the population and the global economy. As COVID-19 is studied, new data are emerging regarding the risk of severe coronavirus infection in patients with α1-antitrypsin deficiency.
A. L. Kravtsov, S. A. Bugorkova
doaj   +1 more source

Total hip and knee replacement surgery results in changes in leukocyte and endothelial markers

Journal of Inflammation, 2010
Background It is estimated that over 8 million people in the United Kingdom suffer from osteoarthritis. These patients may require orthopaedic surgical intervention to help alleviate their clinical condition. Investigations presented here was to test the
Maclean Kirsty M, Edwards David R, Hendricks Beverly D, Hughes Stephen F, Bastawrous Salah S, Middleton Jim F   +5 more
doaj   +1 more source

Isolation and Characterization of Porcine Leukocyte Elastase. Leukocyte Elastase-Inhibitor Complexes in Porcine Blood, II [PDF]

Clinical Chemistry and Laboratory Medicine, 1985
Porcine leukocyte elastase was purified from granulocytes by chelating chromatography on copper chelate Sepharose and by ion exchange chromatography on CM-Sepharose. Thus an enzyme preparation with a specific activity (substrate: MeOSuc(Ala)2ProValNan) of 89.3 U/mg protein was obtained.
Geiger, R., Junk, Anni, Jochum, Marianne
openaire   +3 more sources

Correlations between different protein species of oral rinse MMP‐8 and patient‐related factors

Clinical and Experimental Dental Research, 2023
Objectives The aim of this study is to examine correlations between different oral rinse matrix metalloproteinase (MMP)‐8 protein species in western blot (WB) analysis, quantitative MMP‐8 measurements, and patient‐related factors.
Jussi M. Leppilahti, Taina Tervahartiala, Hannu Kautiainen, Ismo Räisänen, Minna‐Maija Ahonen, Veli‐Jukka Uitto, Timo Sorsa, Päivi Mäntylä   +7 more
doaj   +1 more source

Investigation of Midtrimester Amniotic Fluid Factors as Potential Predictors of Term and Preterm Deliveries

Mediators of Inflammation, 2006
Aims. Our aim is to investigate, in 13 cases (delivering preterm) and 21 matched (for age, parity, and gestational age) controls (delivering at term), whether midtrimester amniotic fluid concentrations of elastase, secretory leukocyte proteinase ...
Ariadne Malamitsi-Puchner, Nikolaos Vrachnis, Evi Samoli, Stavroula Baka, George Alexandrakis, Karl-Philipp Puchner, Zoe Iliodromiti, Demetrios Hassiakos   +7 more
doaj   +2 more sources

Indigenous enzymes and leukocyte in sheep milk are markers of health status and physiology of the mammary gland

Italian Journal of Animal Science, 2010
Plasmin, plasminogen and plasminogen activator in ewe bulk milk were not significantly affected by stage of lactation probably as a consequence of the good health of the ewe udders throughout lactation as indicated by SCC which never exceeded 600,000 ...
Agostino Sevi, Laura Schena, Alessandra Marzano, Francesca D’Angelo, Marzia Albenzio   +4 more
doaj   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

A Proteinase 3 Contribution to Juvenile Idiopathic Arthritis-Associated Cartilage Damage

Pathophysiology, 2021
A full understanding of the molecular mechanisms implicated in the etiopathogenesis of juvenile idiopathic arthritis (JIA) is lacking. A critical role for leukocyte proteolytic activity (e.g., elastase and cathepsin G) has been proposed.
Eric K. Patterson, Nicolas Vanin Moreno, Douglas D. Fraser, Gediminas Cepinskas, Takaya Iida, Roberta A. Berard   +5 more
doaj   +1 more source