Results 101 to 110 of about 75,140 (320)

Neutrophil extracellular traps-inspired DNA hydrogel for wound hemostatic adjuvant

Nature Communications
Severe traumatic bleeding may lead to extremely high mortality rates, and early intervention to stop bleeding plays as a critical role in saving lives.
Rui Ye, Ziyu Zhu, Tianyi Gu, Dengjie Cao, Kai Jiang, Qiang Dai, Kuoran Xing, Yifan Jiang, Siyi Zhou, Ping Cai, D. Leong, Mengfei Yu, Jie Song   +12 more
semanticscholar   +1 more source

The role of neutrophil extracellular traps in acute lung injury

Frontiers in Immunology, 2022
Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high morbidity and mortality. Neutrophils play a key role in the development of different forms of ALI, and the release of neutrophil extracellular traps (NETs) is emerging
D. Scozzi, Fuyi Liao, A. Krupnick, D. Kreisel, A. Gelman   +4 more
semanticscholar   +1 more source

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

Advanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji, Ruichen Zhang, Dongyi Xu, Patrick C. A. van der Wel, Alessia Lasorsa, Guotai Li, Fangze Guo, Qihui Zhou, Patrick van Rijn   +8 more
wiley   +1 more source

NETosis and Neutrophil Extracellular Traps in COVID-19: Immunothrombosis and Beyond

Frontiers in Immunology, 2022
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-19) pandemic, causes respiratory problems and multifaceted organ dysfunction.
Yuanfeng Zhu, Xiaoli Chen, Xin Liu
semanticscholar   +1 more source

Hypoxia increases neutrophil-driven matrix destruction after exposure to Mycobacterium tuberculosis. [PDF]

, 2018
The importance of neutrophils in the pathology of tuberculosis (TB) has been recently established. We demonstrated that TB lesions in man are hypoxic, but how neutrophils in hypoxia influence lung tissue damage is unknown.
A Dorhoi, A Mantovani, AM Houghton, AM McInturff, C Peyssonnaux, CW Ong, CW Ong, D Nickel, J Rius, JE Galagan, JM McCracken, K Dheda, K Ostridge, K Steinwede, LW Garratt, M Datta, MP Berry, N Borregaard, N Branzk, NN McGovern, PM Elks, PM Elks, PT Elkington, PT Elkington, PT Elkington, PT Elkington, S Aliberti, SC Cheng, SH Kaufmann, SH Oehlers, SR Walmsley, SS Shell, ST Reece, SY Eum, TA Fuchs, V Nizet, V Ramos-Kichik   +36 more
core   +1 more source

Neutrophil extracellular traps in bacterial infections and evasion strategies

Frontiers in Immunology
Neutrophils are innate immune cells that have a vital role in host defense systems. Neutrophil extracellular traps (NETs) are one of neutrophils’ defense mechanisms against pathogens. NETs comprise an ejected lattice of chromatin associated with histones,
Ahmed Adel Baz, Huafang Hao, Shimei Lan, Zhangcheng Li, Shuang Liu, Shengli Chen, Yuefeng Chu   +6 more
semanticscholar   +1 more source

Elevated neutrophil extracellular traps by HBV‐mediated S100A9‐TLR4/RAGE‐ROS cascade facilitate the growth and metastasis of hepatocellular carcinoma

Cancer Communications, 2022
Neutrophil extracellular traps (NETs) are considered significant contributors to cancer progression, especially metastasis. However, it is still unclear whether NETs are involved in hepatitis B virus (HBV)‐related hepatocarcinogenesis and have potential ...
Xiaohui Zhan, R. Wu, Xueying Kong, Yan You, K. He, Xiaoyu Sun, Yong Huang, Wei-Xian Chen, Liang Duan   +8 more
semanticscholar   +1 more source

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source

Neutrophil extracellular traps in chronic lung disease: implications for pathogenesis and therapy

European Respiratory Review, 2022
Neutrophilic inflammation has a key role in the pathophysiology of multiple chronic lung diseases. The formation of neutrophil extracellular traps (NETs) has emerged as a key mechanism of disease in neutrophilic lung diseases including asthma, COPD ...
Holly R. Keir, J. Chalmers
semanticscholar   +1 more source