Results 101 to 110 of about 52,667 (297)

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

Advanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li, Tianfang Wang, Nicolas Soro, Guoying Ni, Meg Allom, D. İpek Kurtböke, Xiaosong Liu, Damon Kent   +7 more
wiley   +1 more source

Studies on the release of neutrophil extracellular traps and IFN-γ as part of the innate immune response to Aspergillus fumigatus and on the fungal stress response via the hybrid sensor kinase TcsC [PDF]

, 2012
Aspergillus fumigatus is a saprophytic mold that naturally inhabits the soil. Asexual reproduction yields hardy conidia that circulate in the air and are inhaled daily by humans.
McCormick, Allison
core  

Hypoxia increases neutrophil-driven matrix destruction after exposure to Mycobacterium tuberculosis. [PDF]

, 2018
The importance of neutrophils in the pathology of tuberculosis (TB) has been recently established. We demonstrated that TB lesions in man are hypoxic, but how neutrophils in hypoxia influence lung tissue damage is unknown.
A Dorhoi, A Mantovani, AM Houghton, AM McInturff, C Peyssonnaux, CW Ong, CW Ong, D Nickel, J Rius, JE Galagan, JM McCracken, K Dheda, K Ostridge, K Steinwede, LW Garratt, M Datta, MP Berry, N Borregaard, N Branzk, NN McGovern, PM Elks, PM Elks, PT Elkington, PT Elkington, PT Elkington, PT Elkington, S Aliberti, SC Cheng, SH Kaufmann, SH Oehlers, SR Walmsley, SS Shell, ST Reece, SY Eum, TA Fuchs, V Nizet, V Ramos-Kichik   +36 more
core   +1 more source

Cap‐oPMN: Oral Inflammatory Load Quantification Using Capillary Microfluidics and Automated Image Processing

Advanced Materials Technologies, EarlyView.
ABSTRACT Quantifying oral polymorphonuclear neutrophils (oPMNs) is a clinically validated approach for assessing periodontal inflammation. However, current methods, such as manual hemocytometry and flow cytometry, are time‐consuming (>3 h), require invasive sampling, and depend on staining and complex instrumentation, making them unsuitable for point ...
Mohsen Hassani, Azam Zare, Fatemeh Soheili, S. M. Mahdi H. Daneshvar, Mahdi Amrollahi Biouki, Yasaman Tahernezhad, Chunxiang Sun, Michael Glogauer, Ebrahim Ghafar‐Zadeh, Amir Sanati‐Nezhad   +9 more
wiley   +1 more source

Macrophage Migration Is Impaired within Candida albicans Biofilms [PDF]

, 2017
Acknowledgments: We thank the Microscopy and Histology Core Facility at the University of Aberdeen. This work was funded by NHS Grampian Endowments (grant RG10191); the Wellcome Trust Strategic Award in Medical Mycology and Fungal Immunology (grant ...
Alonso, Maria F., Bain, Judith M., Erwig, Lars P., Gow, Neil A. R.   +3 more
core   +2 more sources

Information Transmission Strategies for Self‐Organized Robotic Aggregation

Advanced Robotics Research, EarlyView.
In this review, we discuss how information transmission influences the neighbor‐based self‐organized aggregation of swarm robots. We focus specifically on local interactions regarding information transfer and categorize previous studies based on the functions of the information exchanged.
Shu Leng, Zihan Li, Yifeng Shao, Jinhao Liu, Li Yu, Shuguang Li   +5 more
wiley   +1 more source

Regulation of Pseudomonas aeruginosa-Mediated Neutrophil Extracellular Traps

Frontiers in Immunology, 2019
Pseudomonas aeruginosa is the most prevalent opportunistic pathogen in the airways of cystic fibrosis (CF) patients. The pulmonary disorder is characterized by recurrent microbial infections and an exaggerated host inflammatory immune response led ...
Sladjana Skopelja-Gardner, Jomkuan Theprungsirikul, Kimberley A. Lewis, John H. Hammond, Kyrsten M. Carlson, Haley F. Hazlett, Amanda Nymon, Dao Nguyen, Brent L. Berwin, Deborah A. Hogan, William F. C. Rigby, William F. C. Rigby   +11 more
doaj   +1 more source

Activation of conventional protein kinase C (PKC) is critical in the generation of human neutrophil extracellular traps [PDF]

, 2013
BACKGROUND: Activation of NADPH oxidase is required for neutrophil extracellular trap (NET) formation. Protein kinase C (PKC) is an upstream mediator of NADPH oxidase activation and thus likely to have a role in NET formation.
Davidson, Donald J, Gray, Robert D, Haslett, Chris, Hiersemenzel, Katia, Li, Feng, Lucas, Christopher, Mackellar, Annie, Rossi, Adriano G   +7 more
core   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

Advanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo, Shuai He, Shirui Chen, Dongmei Ye, Shibo Zhang, Di Liu, Dawei Zou, Linhe Wang, Huadi Chen, Jinghong Xu, Huanjie Liu, Ruiting Liu, Xi Tan, Yitong Wang, Jiayi Zeng, Runbing Mo, Yuexin Li, Yuyi Zhang, Tanyiyang Ruan, Tielong Wang, Zehua Jia, Yu Jia, Tongdi Fang, Yimou Lin, Xiaorui Liu, Yunhua Tang, Maogen Chen, Qiang Zhao, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Schlegel Andrea, Yuan Zhai, Kwan Man, Tullius G. Stefan, Yifang Gao, Jinxin Bei, Xiaoshun He, Zhiyong Guo   +40 more
wiley   +1 more source

Neutrophil Extracellular Traps, Antiphospholipid Antibodies and Treatment

Antibodies, 2017
Neutrophil extracellular traps (NETs) are a network of extracellular fibers, compounds of chromatin, neutrophil DNA and histones, which are covered with antimicrobial enzymes with granular components.
Jessica Bravo-Barrera, Maria Kourilovitch, Claudio Galarza-Maldonado   +2 more
doaj   +1 more source