Results 201 to 210 of about 32,634 (246)

Chromosomal and immune dysregulation underlying granular mitosis in glioblastoma

Brain Pathology, EarlyView.
Granular mitosis (GM) morphology is linked to PI3K/PTEN pathway alterations, chromosomal disorganization, and impaired innate immunity. Cells exhibiting GM morphology are associated with localized immune responses within their immediate spatial microenvironment.
Rachel Barboza, Xuan Wang, August Lin, Eric Liu, Pramath Kakodkar, Yayuan Zhao, Quinn Le, Christina A. Castellani, Qi Zhang   +8 more
wiley   +1 more source

Neutrophil Extracellular Traps in Pancreatic Ductal Adenocarcinoma: A Vicious Cycle in the Tumor Microenvironment and Targeted Interventions. [PDF]

Int J Biol Sci
Zhao L, Yuan H, Chen Z, Xia X, Tian X, Wang S.   +5 more
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Neutrophil extracellular traps in the tumor microenvironment, metastasis, therapy, and beyond: advances, challenges, and perspectives. [PDF]

J Hematol Oncol
He J, Zhou Z, Cheng G, Li H, Tu J, Fan Z, Qiu X, Chen W, Chen Y, Li L, Li C, Li Z, Chen L, Lu Q.   +13 more
europepmc   +1 more source

Simplified flow cytometric quantification of human neutrophil extracellular traps (NETs). [PDF]

J Inflamm (Lond)
Rinaldi G, Cheng KKW, McCann C, Rossi F, Rodriguez-Rios M, Dhaliwal K, Bebes A, Duncan L, Yuecel R, Rossi AG, Robb CT.   +10 more
europepmc   +1 more source

Neutrophils and neutrophil extracellular traps in diabetes mellitus and its complications: Mechanisms and therapeutic implications. [PDF]

iScience
Lei L, Liu J, Li Y, Huang B, Zou Z.
europepmc   +1 more source

Neutrophil extracellular traps in gynecological disease: pathogenic mechanisms and therapeutic opportunities. [PDF]

Front Med (Lausanne)
Wu M, Ding J, Zhang X.
europepmc   +1 more source

Neutrophil Extracellular Traps in Cancer Metastasis: From Mechanistic Understanding to Targeted Therapy. [PDF]

Curr Oncol
Tian X, Na J, Tan X, Dang F, Zhu R, Zhong L, Zhao Y.   +6 more
europepmc   +1 more source