Results 211 to 220 of about 32,634 (246)

Automated flow cytometric quantification of human neutrophil extracellular traps (NETs)

open access: yes
Rinaldi G   +10 more
europepmc   +1 more source

Neutrophil extracellular traps in cancer

Seminars in Cancer Biology, 2022
Beyond their well-known functions in the acute phases of the immune response, neutrophils play important roles in the various phases of tumor initiation and progression, through the release of their stored or newly synthesized mediators. In addition to reactive oxygen species, cytokines, chemokines, granule proteins and lipid mediators, neutrophil ...
Leonardo Cristinziano   +6 more
openaire   +3 more sources

Rethinking neutrophil extracellular traps

International Immunopharmacology, 2023
Neutrophils are a major subset of leukocytes in human circulating blood. In some circumstances, neutrophils release neutrophil extracellular traps (NETs). lnitially, NETs were considered to have a strong antibacterial capacity. However, currently, NETs have been shown to have a pivotal impact on various diseases.
Yi Liu   +10 more
openaire   +2 more sources

Neutrophil extracellular traps: neutrophil’s afterlife

Hirurg (Surgeon), 2021
This paper is a literature review on the origin, structure and functioning of neutrophil extracellular traps (NETs) that are released from neutrophils through NETosis, the kind of cell death. NETs are comprised of DNA, histones and neutrophil granule enzymes.
Olga Yaroslavna Porembskaya   +7 more
openaire   +1 more source

Extracellular neutrophil traps in periodontitis

Journal of Periodontal Research, 2009
Background and Objective:  Chronic periodontitis, the chronic inflammatory disease of the periodontium, is caused by bacteria and is characterized by an influx of neutrophils into the gingival crevice. Recently, a ‘new’ extracellular neutrophil defense mechanism – neutrophil extracellular traps – has been described. However, their role in periodontitis
L, Vitkov   +3 more
openaire   +2 more sources

Neutrophil Extracellular Traps in Sepsis

Shock, 2014
Sepsis is the leading cause of death in critically ill patients in intensive care units. Early recognition of sepsis and proper therapy are essential to reduce patient mortality. Moreover, treatment options for this deleterious inflammatory response to infection are limited.
Camicia, Gabriela Lorena   +2 more
openaire   +3 more sources

Neutrophil Extracellular Traps Kill Bacteria

Science, 2004
Neutrophils engulf and kill bacteria when their antimicrobial granules fuse with the phagosome. Here, we describe that, upon activation, neutrophils release granule proteins and chromatin that together form extracellular fibers that bind Gram-positive and -negative bacteria. These neutrophil extracellular traps (NETs) degrade virulence factors and kill
Brinkmann, V.   +7 more
openaire   +4 more sources

Neutrophil extracellular traps and neutrophilic asthma

Respiratory Medicine
There are more than 260 million asthma patients worldwide. How to provide targeted long-term standardized treatment and management still confuses clinical workers and patients. Neutrophilic asthma is a special type of asthma which is difficult to diagnose clinically and often associated with severe asthma and glucocorticoid resistance.
Jiayi, Xiang, Muyan, Cui, Yuling, Zhang
openaire   +2 more sources

Neutrophil Extracellular Trap in Human Diseases

2012
NETosis is a unique death pathway that differs from apoptosis and necrosis and depends on the generation of reactive oxygen species (ROS) by NADPH oxidase. During this process, neutrophil extracellular traps (NETs) are created. NETs are extracellular structures composed of chromatin and variety of proteins from cells granules that bind and kill ...
Araźna, Magdalena   +3 more
openaire   +2 more sources

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